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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Noggin is necessary to start the hair growth phase in skin after birth.

Androgens can both increase and decrease hair growth in different parts of the body.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

PGD2 stops hair growth and is higher in bald men with AGA.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

New effective scar treatments are urgently needed due to the current options' limited success.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

CDP is crucial for lung and hair follicle cell development.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Chemotherapy-induced hair loss significantly affects patients' well-being, and nurses are key in helping them cope, but more research is needed to find effective treatments.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Peptide hydrogels heal burn wounds faster and better than standard dressings.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.