Search

everythinglearnresearchcommunity

for

Search:↓

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

Method detects finasteride in plasma at very low concentrations.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Hair cortisol levels can show increased stress during late pregnancy but only for up to six months.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.

Medium-sized particles penetrate hair follicles better than smaller or larger ones, which could improve delivery of skin treatments.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

The Rotterdam Study aims to understand various diseases in older adults.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Androgens can both increase and decrease hair growth in different parts of the body.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.