122 citations
,
July 1990 in “Teratology” This study found that oral administration of finasteride to pregnant rats caused dosage-related developmental toxicities, including hypospadias and decreased anogenital distance in male offspring.
96 citations
,
January 1997 in “Clinics in Dermatology” This study found that G protein-coupled estrogen receptor enhances melanin synthesis in melanoma cells through cAMP-PKA-MITF-TYR signaling, suggesting its potential as a drug target for chloasma treatment.
78 citations
,
June 2021 in “Dermatology and Therapy” This study highlights the evolving understanding of acne's pathophysiology and suggests that targeting pro-inflammatory cytokines such as IL-1β, IL-17, IL-23, and TNFα with biological antibodies may offer new treatment strategies for severe acne and its scars.
71 citations
,
February 2006 in “Clinics in Dermatology” This review discusses the physiological skin changes during pregnancy and reports no new clinical results, emphasizing the importance of distinguishing these changes from pathological conditions.
52 citations
,
February 2012 in “Plastic Surgery International” This review describes techniques for successful skin grafting and variations of the procedure, reporting no new clinical results.
51 citations
,
February 2006 in “Clinics in Dermatology” This review discusses the physiological changes in the female body during pregnancy, relating them to hormonal shifts, and comments on treatment considerations, but it presents no new research findings.
36 citations
,
June 2018 in “Journal of Dermatology” This article updates Japanese guidelines for diagnosing and treating male and female-pattern hair loss, recommending specific drugs and therapies while advising against certain treatments for female-pattern hair loss.
34 citations
,
May 2013 in “Journal of the European Academy of Dermatology and Venereology” In this study, changes in hair cycle phases during pregnancy and the post-partum period showed a rise in telogen rates after delivery, especially among non-breastfeeding women, but no drastic exaggerations were noted.
28 citations
,
January 1991 in “Reproductive Toxicology” Finasteride temporarily lowers male rat fertility without affecting libido.
24 citations
,
June 2011 in “International Journal of Dermatology” This review summarizes physiologic skin changes during pregnancy and specific pregnancy-related dermatoses but reports no new clinical results.
19 citations
,
January 2001 in “Dermatology + psychosomatics” This review discusses the perceptions of male pattern baldness by strangers and explores the sociocultural aspects of hair and hair loss but reports no new results.
18 citations
,
February 2010 in “Odontology” This report describes Rabson-Mendenhall syndrome cases in two siblings and briefly reviews the literature, highlighting insulin receptor gene mutations as the underlying cause.
18 citations
,
April 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This review explores the potential genetic and epigenetic influences on hair whorl patterns and suggests that pattern formation may involve basic physical-chemical laws, although it reports no new experimental findings.
17 citations
,
April 1997 in “Archives of dermatology” This case report describes the treatment of hirsutism in a 15-year-old obese Mexican girl with flutamide, aiming to improve her social function.
15 citations
,
June 1995 in “The American Journal of the Medical Sciences” This study describes a case where finasteride treatment for benign prostatic hypertrophy was associated with gynecomastia in a 62-year-old man, which resolved after the drug was discontinued.
13 citations
,
March 2018 in “Journal of Sociology” This article argues that the promissory discourse in the anti-ageing treatments market exploits societal anxieties about ageing, but its long-term sustainability is questionable as many promises remain undeliverable.
12 citations
,
January 2010 in “PubMed” This article summarizes the MHRA report on finasteride and does not present new clinical findings.
11 citations
,
February 2013 in “Clinical Endocrinology” This study found that the prevalence of hyperprolactinaemia in healthy premenopausal female blood donors is low and not affected by hormonal contraceptive use, with stress-related factors being the most common cause.
10 citations
,
June 2016 in “Wound Repair and Regeneration” This review explores the regenerative potential of hair follicles and their role in complete skin regeneration, emphasizing the influence of mechanical factors and niche signaling pathways on hair growth and loss.
9 citations
,
August 1952 in “The Journal of Clinical Endocrinology & Metabolism” This study describes a method to estimate endogenous hormone production by neutralizing an endogenous hormone with an oppositely acting hormone.
7 citations
,
August 2018 in “South African Medical Journal” This article provides a comprehensive overview of tattoo-related issues for clinicians, covering various aspects such as tattoo types, medical relevance, removal methods, complications, and South African legislation, but reports no new research findings.
4 citations
,
September 2014 in “Elsevier eBooks” This review discusses the safety of dermatological medications used during pregnancy, highlighting that retinoids have strong teratogenic risks and should be used with caution; it reports no new clinical results.
3 citations
,
June 2018 in “International Journal of Clinical Pharmacy” In this case report, maternal use of finasteride during early pregnancy was not associated with external genitalia abnormalities in a male infant, but the findings are limited to one case and broader safety conclusions cannot be drawn.
3 citations
,
April 2012 in “Bioinformation” This study concluded that specific SNPs in the TRPS1 gene significantly alter its protein structure, affecting interactions and contributing to the development of congenital hypertrichosis.
2 citations
,
July 2019 in “PLOS ONE” This study found that the CYP3A4 rs4646437 genotype was significantly associated with ALT elevation in Japanese patients undergoing asunaprevir plus daclatasvir therapy for chronic HCV infection, suggesting genotyping may help in monitoring patients safely.
2 citations
,
June 2019 in “Facial Plastic Surgery” This review discusses the use of medical tattooing in the head and neck region as a minimally invasive option for individuals seeking to improve cosmetic appearance without surgery, and reports no new clinical results.
2 citations
,
October 2018 in “The journal of pediatrics/The Journal of pediatrics” This case report identified a 4-month-old boy with Menkes disease, a neurodegenerative disorder of copper metabolism, noting symptoms like recurrent seizures, developmental delay, and specific physical characteristics, confirmed by genetic sequencing showing a pathogenic ATP7A mutation and low serum copper and ceruloplasmin levels.
1 citations
,
July 2019 in “The journal of applied laboratory medicine” This review analyzes 873 cases of female hyperandrogenism, primarily attributing it to polycystic ovarian syndrome, and explores sample testing for suspected neoplasms but reports no new clinical findings.
1 citations
,
July 2019 in “Journal of the Dermatology Nurses' Association” This article discusses highlights from the 2019 Dermatology Nurses' Association's annual meeting, covering various dermatological conditions and treatments, and reports no new clinical findings.
1 citations
,
December 2013 in “Urological Science” This case report documents a 59-year-old man in Taiwan who developed breast cancer while undergoing finasteride therapy for benign prostate hyperplasia, marking a rare side effect.