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This study developed a new finasteride release system using chitosan-based nanoniosomes, observing that 70% of the drug was released over ten days in vitro, suggesting potential for prostate cancer prevention.

In this study, researchers found that niosomes, bilosomes, and spanlastic formulations can enhance the oral anticoagulation efficiency of rivaroxaban in rats, with spanlastic ranked as the most effective in prolonging clotting, prothrombin, and tail bleeding times compared to unprocessed rivaroxaban.

This study found that minoxidil-loaded niosomes with a Span 60 and cholesterol ratio of 1:2 significantly increased skin retention of minoxidil compared to control gel.

This review explores research on nanoformulations for enhancing the topical delivery of herbal medicines, noting potential benefits like improved bioavailability and sustained delivery, and emphasizes the need for safety and toxicity guidelines in developing these novel drug delivery systems.

This review discusses the research and development of vesicular carriers to enhance the delivery and effectiveness of active ingredients in cosmetic products, reporting no new clinical results.

This review systematically examined recent advancements in spironolactone-loaded nanocarriers, revealing that lipid and vesicular nanoparticles enhance bioavailability and skin penetration for treating androgen-dependent disorders, but highlighted the need for further clinical studies to optimize their use.

In this study, loading niosomes with Oryza sativa bran extract altered their physical properties, suggesting potential for developing formulations aimed at anti-hair loss products.

This study found that PEGylated LUT-Aspasomes significantly improved neuroprotective effects in stressed rats, enhancing spatial memory, reducing depressive-like behavior, and preserving hippocampal architecture better than free luteolin. Additionally, it increased brain delivery and stability, suggesting potential for treating stress-related neurobehavioral disorders.

This review highlighted recent advances in nanocarrier-based topical delivery systems for skincare, emphasizing their potential to enhance ingredient stability, penetration, and targeted release while addressing specific pathophysiological skin concerns.

This study demonstrated that a new topical treatment using ketotifen-loaded microneedles, designed for prolonged release, significantly reduced inflammatory markers in an animal model of allergic conjunctivitis, suggesting enhanced therapeutic delivery and sustained ocular benefits.

Repaglinide-loaded liponiosomal hybrids improve blood sugar control and insulin release better than regular Repaglinide.

This study found that CoQ10 formulated in transethosomes showed improved penetration and a better clinical response in treating androgenic alopecia compared to CoQ10 solution.

This review explores nano-quercetin formulations to enhance the solubility, stability, and targeted delivery of quercetin, highlighting its potential efficacy in treating cancer, inflammation, metabolic diseases, and tissue regeneration, though challenges in biocompatibility, toxicity, and production remain, per this source.

This review study found that vesicular carriers like liposomes, niosomes, invasomes, and transferosomes can enhance drug penetration through follicles, benefiting treatments for alopecia, acne, and infections, as well as potentially facilitating systemic delivery of antihypertensive drugs and insulin.

This review discusses various nanoparticles and nanoemulsions being investigated for transdermal drug delivery and reports no clinical results; it highlights potential applications in treating alopecia, wound healing, psoriasis, and melanoma.

This review highlights recent advancements in using niosomes as nanocarriers for improved delivery and sustained release of active cosmetic compounds, discussing their properties, applications, and future potential in cosmetic chemistry.

This review explores the application of nanotechnology in cosmetics, highlighting its role in enhancing skin penetration, sustaining drug action, and protecting against UV radiation, while also addressing regulatory considerations and potential exposure routes.

This review discusses various nanoparticles used to enhance skin permeation and target delivery to skin organelles, but reports no new experimental results.

This review explores the use of topical and transdermal delivery for drugs and cosmetics, highlighting the benefits of avoiding side effects and rapid metabolism, with a focus on nanoparticulate formulations and techniques for studying skin penetration.

This study focused on designing a niosome formulation that encapsulates pumpkin seed oil for topical use, achieving high entrapment efficiency and stability over three months.

This review highlights the challenges in developing nano-scale drug delivery systems for natural antioxidants in wound healing, pointing out issues like low solubility and skin permeability, and discusses potential solutions such as combining polymers and lipids to enhance delivery effectiveness.

This study found that formulating raloxifene in nano-lipid carriers significantly enhanced its permeation and cytotoxicity against cancer cells compared to raw raloxifene.

This review highlights the potential of ellagic acid for treating various skin conditions due to its antioxidant, anti-inflammatory, and depigmenting properties, but notes that novel formulations are needed to overcome its poor solubility and skin permeability to enhance clinical efficacy.

Niosomes are a promising and effective way to deliver drugs through the skin.

This chapter reviews nanotechnology in cosmetics, detailing various formulations, performance assessment methods, and evolving regulations, while discussing safety, stability, and effectiveness concerns; it reports no new experimental results.

This review discusses niosomes' increasing popularity in dermatology for topical drug delivery due to their ability to enhance drug penetration, provide sustained release, and carry various drugs, while reporting no new clinical findings.

This study developed a niosomal delivery system loaded with tretinoin and bicalutamide, optimized for follicular targeting in acne management, showing promising accumulation in hair follicles in animal models.

This study suggests that gel containing OSF3 loaded in niosomes offers high transfollicular penetration for topical anti-androgenic alopecia treatment with minimal systemic effect.

The study explored niosome formulations containing minoxidil and tretinoin and found increased drug stability and controlled release, suggesting potential as an effective drug delivery system for treating hair loss.

This review explores the effects of caffeine on cancer, cardiovascular, immunological, inflammatory, and neurological diseases, including its use in sports, and discusses advancements in caffeine delivery through novel nanocarrier-based formulations.