2 citations,
February 2022 in “Human Gene Therapy” Increasing miR-149 reduces hair follicle stem cell growth and hair development by affecting certain cell growth pathways.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Primary cilia affect the size and oil production of eye glands but not the oil's makeup.
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
24 citations,
March 2020 in “Cells” Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.
5 citations,
October 2022 in “Cosmetics” Cell-based models help test if cosmetic ingredients really work for hair growth and skin health.
18 citations,
September 2020 in “International Journal of Nanomedicine” Both human and animal-derived small extracellular vesicles speed up skin healing equally well.
15 citations,
February 2021 in “Scientific Reports” RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.
1341 citations,
January 2014 in “Cardiology Research and Practice” Managing metabolic syndrome needs both lifestyle changes and medical treatments.
204 citations,
October 1999 in “EMBO journal” Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.
103 citations,
June 2018 in “International Journal of Molecular Sciences” FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.
50 citations,
January 2016 in “The Journal of Clinical Endocrinology and Metabolism” Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.
41 citations,
January 2020 in “Journal of Ovarian Research” Quercetin may help with PCOS symptoms, but more research is needed.
32 citations,
January 2021 in “Molecules” Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.
31 citations,
February 2021 in “Nutrients” Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.
23 citations,
August 2018 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
13 citations,
January 2021 in “RSC chemical biology” Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
4 citations,
June 2018 in “PLOS ONE” Iron levels are linked to insulin resistance in men and postmenopausal women, but not in premenopausal women.
369 citations,
June 2013 in “Biochimie” Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.
88 citations,
December 2018 in “Advanced Healthcare Materials” Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.
18 citations,
September 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” VDUP1 is found in skin and hair follicles, interacts with sciellin, and may help regulate skin cell differentiation.
17 citations,
December 2010 in “Journal of Investigative Dermatology” Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.
13 citations,
December 1991 in “Annals of the New York Academy of Sciences” Researchers created a lab model to study human hair growth, showing it can grow and self-regulate outside the body.
70 citations,
March 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.
62 citations,
July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
28 citations,
January 2018 in “Biochemical Society Transactions” Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.
28 citations,
September 2015 in “Wiener Klinische Wochenschrift” New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
22 citations,
November 2008 in “International Journal of Dermatology” A mix of 5-aminolevulinic acid and iron ion can speed up hair growth.
4 citations,
November 2015 in “Journal of Investigative Dermatology” Testosterone may worsen hair loss by affecting hair growth signals, while different prostaglandins can either hinder or promote hair growth.
1 citations,
December 2023 in “Curēus” Tadalafil is effective for treating urinary symptoms in men with BPH.
May 1995 in “Journal of Investigative Dermatology” Researchers developed a new way to measure gene activity in single hair follicles and found that a specific gene's activity changes with different amounts and times of treatment.