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The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Fungi-produced compounds can change plant root growth.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Researchers created human hair follicles using a new method that could help treat hair loss.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Telocytes might help with skin repair and regeneration.

Blocking JAK-STAT signaling can lead to hair growth.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.