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This chapter reviews recent findings on androgen receptor function, structure, and interactions, highlighting post-translational modifications and mutations related to prostate cancer, but reports no new experimental results.

This study found that black and Hispanic women had higher odds of self-reported alopecia areata compared to white women, highlighting potential racial disparities in the condition's occurrence.

This study found that DHT treatment led to reduced cell growth, increased cell death, cell cycle arrest, ROS production, and senescence in normal human dermal papilla cells, potentially mediated by altered miRNA expression.

This study concluded that an adapalene nanohydrogel containing Tween-80 could be a promising and stable topical treatment option for acne vulgaris due to enhanced skin permeability and stability compared to other formulations.

This study found that patients with alopecia areata had an increased risk of mortality from self-harm, psychiatric diseases, and lung cancer compared to the general population.

This study found that UVB radiation significantly alters miRNA expression and induces cytotoxicity and apoptosis in normal human dermal papilla cells.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

This article describes the synthesis of novel polyamine-modified minoxidil analogs and conjugates to potentially enhance minoxidil's biological activity, selectivity, and water solubility, but reports no new biological results.

This study demonstrated that combining l-cystine and thiamin in a formulation may protect against UV-induced damage in growth-limited human epidermal keratinocytes in vitro.

This meta-analysis reported that individuals who frequently use hair dye or have used it for over 20 years have an increased risk of developing non-Hodgkin's lymphoma.

This study found that human dermal fibroblasts can promote the viability and proliferation of microvascular endothelial cells in vitro, revealing important interactions at play in hair growth.

In this study, saponins from Korean red ginseng were found to protect against the harmful effects of airborne particulate matter on human skin cells by reducing oxidative stress, inflammation, leptin expression, and melanin production.

This study found that epidermolysis bullosa simplex keratinocytes had impaired mitochondrial activity and more dispersed mitochondrial distribution compared to normal human keratinocytes.

This article reviews the role of enzymatic processes in drug and toxin metabolism, emphasizing their impact on solubility and elimination, without presenting new clinical findings.

This study developed a new melanocyte cultivation medium without chemical mitogens, melanogenesis enhancers, or bovine products, demonstrating successful proliferation and melanotic differentiation of human melanocytes from hair follicles.

This study found that a cosmetic foam reduced the telogen rate in men with androgenetic alopecia, suggesting a potential benefit against male pattern hair loss.

This review discusses recent advancements in the development and use of polymer-based nanohydrogels for topical drug delivery, noting their potential to enhance drug loading, release control, and skin penetration for treating dermatological conditions.

This pilot study found that intradermal 10% glucose combined with non-cross-linked hyaluronic acid improved hair density and diameter more than hyaluronic acid alone in adults with androgenetic alopecia, with no serious adverse events.

This study found that nestin-expressing hair follicle-derived cells express higher levels of certain neurotrophic factors and neural markers, indicating potential for neuroregenerative therapy applications.

This retrospective audit found that patients with alopecia areata often experience significant psychological distress, yet proper mental health assessments and referrals to support services are infrequently conducted, highlighting a gap between current practice and guideline recommendations for comprehensive care.

This study detailed the implementation of an autonomous AI device in an NHS skin cancer pathway, showing that it achieved a sensitivity of 97.3% for diagnosing skin cancers and exceeded sensitivity targets compared to specialists with a negative predictive value over 99.7%.

In this study, researchers reviewed wig prescribing practices for alopecia at a single center and found a high demand for wigs, especially acrylic ones, and noted significant funding discrepancies between different regions, emphasizing their importance in managing patient wellbeing on the NHS.

In this study, researchers found that the protein eIF4E is crucial for keratinocyte proliferation in psoriasis, suggesting it as a potential treatment target for the condition.

This research developed new in vitro models for high-throughput screening of drugs that could protect or restore immune privilege in hair follicles, finding that Tofacitinib was effective in preventing inflammation-related marker upregulation, while Tacrolimus and αMSH worked specifically in outer root sheath keratinocytes.

This study observed that human primary adult hair matrix keratinocytes may have the potential to generate hair follicle organoids, suggesting possible applications in hair follicle neogenesis and preclinical hair growth agent screening.

This study observed that PCE-DP may improve skin pigmentation by increasing epidermal turnover and inhibiting melanin uptake and inflammation in human epidermal keratinocytes.

In this study, the administration of indole-based compounds, particularly L-Tryptophan and Tryptophol, to a PCOS-induced rat model resulted in an increased number of healthy ovarian follicles and a reduction in ovarian cysts compared to untreated rats, suggesting potential therapeutic efficacy.

In laboratory tests and mouse models, this study found that the novel IPC analog SIG-1451 may offer potent anti-inflammatory effects for treating allergic skin inflammation, potentially outperforming some current therapies in specific inflammatory phases.

The researchers reported that iPSCs derived from Sendai virus reprogrammed blood cells can mature into functional keratinocytes for up to 60 days, potentially offering new approaches for DEB treatment.

This study found that COL17 plays a key role in regulating epidermal keratinocyte differentiation and proliferation, influencing the expression of differentiation markers and cellular growth in specific conditions.