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The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

NF-κB is crucial for different stages and types of hair growth in mice.

A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.

The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

Baricitinib reduces inflammation and improves cell health in premature aging cells.

Certain RNA molecules are important for the development of wool follicles in sheep.

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

High levels of testosterone and anti-Müllerian hormone before pregnancy are linked to a higher risk of newborns needing intensive care.

High levels of fatty acids are linked to increased androgen production and inflammation in women with PCOS, which may affect IVF outcomes.

A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.

A20 protein is crucial for normal skin and hair development.

Eating cream can increase ovarian androgen production in women with Polycystic Ovary Syndrome, which is not related to obesity.

African American women have a higher risk of preterm delivery than Caucasian women, and inflammatory stimuli affect gene expression in cells related to PCOS, showing a heightened inflammatory state in women with PCOS.

Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.

Scientists now better understand the genetics of hypohidrotic ectodermal dysplasia, leading to more accurate diagnoses and potential new treatments.

Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.

Botulinum toxin type A significantly reduces scalp psoriasis severity compared to placebo.

Finding new uses for existing drugs is promising and can lead to safer, more effective medicines.

SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Mackerel-derived fermented fish oil helps hair grow by activating growth pathways and increasing cell proliferation.

Indian jujube has many medicinal properties and can help treat ailments like diabetes, inflammation, and cancer.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.