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The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Different types of stem cells and their environments are key to skin repair and maintenance.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Muscles and nerves that cause goosebumps also help control hair growth.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.

Most hair follicle stem cells do not protect their DNA by dividing it unevenly.

RANK-RANKL signaling is essential for hair growth and skin health.

Both mouse and rat models are effective for testing alopecia areata treatments.