7 citations,
August 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” NIPP1 is important for healthy skin and could help treat skin inflammation.
101 citations,
April 2019 in “Cell Stem Cell” Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
85 citations,
March 2018 in “Cell stem cell” Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
16 citations,
March 2021 in “EvoDevo” Different species use the same genes for tooth regeneration.
25 citations,
July 2022 in “Developmental cell” Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
174 citations,
February 2017 in “Cell stem cell” Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
218 citations,
February 2013 in “The Lancet Oncology” Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
52 citations,
April 2013 in “Developmental Cell” Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.
35 citations,
February 2019 in “Cell Communication and Signaling” BMP6 and Wnt10b control whether hair follicles are resting or growing.
25 citations,
November 2018 in “Molecular Biology of the Cell” Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
January 2015 in “Springer eBooks” Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.
321 citations,
March 2015 in “Nature” Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.
191 citations,
September 2011 in “Cell stem cell” Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.
71 citations,
January 2015 in “Journal of molecular cell biology/Journal of Molecular Cell Biology” mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.
31 citations,
January 2014 in “Stem Cells” Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.
9 citations,
January 2020 in “Cell calcium” The STIM1 R304W mutation in mice leads to bone changes and teeth hair growth.
4 citations,
January 2020 in “Cells” The research found that the gene activity in mouse skin stem cells changes significantly as they age.
4 citations,
January 2013 in “Advances in Experimental Medicine and Biology” Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
3 citations,
January 2023 in “Physiological Research” Conditioned media from mesenchymal stem cells show promise for tissue repair and disease treatment, but more research is needed on their safety and effectiveness.
3 citations,
January 2012 in “Wageningen Academic Publishers eBooks” Hair health depends on various factors and hair loss can significantly affect a person's well-being; understanding hair biology is key for creating effective hair care treatments.
2 citations,
April 2020 in “Cell” Elaine Fuchs' research shows how skin stem cells maintain health, aid in healing, and are involved in cancer.
1 citations,
March 2024 in “eLife” TLR2 is important for hair growth and can be targeted to treat hair loss.
1 citations,
August 2023 in “Nature communications” Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
May 2019 in “Journal of Investigative Dermatology” The created skin model with melanoblasts improves the study of skin color and offers an alternative to animal testing.
May 2019 in “Journal of Investigative Dermatology” Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.
May 2019 in “Journal of Investigative Dermatology” Low-level laser therapy helps hair growth and reduces hair loss with few side effects.
759 citations,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
499 citations,
September 2011 in “Cell” Fat-related cells are important for initiating hair growth.
301 citations,
February 2019 in “Nature Communications” The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.
254 citations,
January 2012 in “Nature Reviews Molecular Cell Biology” Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.