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RANKL improves the immune response against herpes simplex virus by enhancing T cell activation and could help develop better treatments or vaccines.

SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.

Leflunomide is effective for rheumatoid arthritis but has significant side effects.

Brg1 is crucial for keeping hair follicle stem cells and repairing skin, working with the Sonic Hedgehog pathway to promote hair growth.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Low oxygen conditions increase the hair-growing effects of substances from fat-derived stem cells by boosting growth factor release.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Microneedling is a safe and effective treatment for various skin conditions, often preferred for its fewer side effects and shorter recovery time.

PDRN helps repair tissue and improve wound healing with a high safety profile.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.

There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.

Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.

Alopecia areata involves immune system imbalances that may lead to depression and anxiety.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.