research Partial Proteasome Inhibitors Induce Hair Follicle Growth by Stabilizing Beta-Catenin
Certain inhibitors applied to the skin can promote hair growth by maintaining a key hair growth signal.
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research Regulatory T Cells: The Many Faces of Foxp3
Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.
research P53-Dependent Transcriptional Regulation of EDA2R and Its Involvement in Chemotherapy-Induced Hair Loss
The study concludes that the EDA2R gene is activated by p53 during chemotherapy but is not necessary for chemotherapy-induced hair loss.
research Wound-Induced Hair Neogenesis: A Novel Paradigm for Studying Regeneration and Aging
Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
research Regulation of Involucrin Gene Expression
Involucrin gene expression is controlled by specific proteins and signaling pathways.
research Adipokines in the Skin and Dermatological Diseases
Adipokines affect skin health and could be targeted for treating skin diseases.
research Molecular Targeted Agents and Biologic Therapies for Non-Small Cell Lung Cancer
New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.
research Alk1 Acts in Non-Endothelial VE-Cadherin+ Perineurial Cells to Maintain Nerve Branching During Hair Homeostasis
Alk1 in specific cells is crucial for proper nerve branching and hair function.
research Leflunomide
Leflunomide is effective for rheumatoid arthritis but has significant side effects.
research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Tissue Regeneration
ePUKs could be valuable for regenerative medicine due to their wound healing abilities.
research Androgenetic Alopecia and Microinflammation
Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
research Pharmacological Activity and Clinical Use of Polydeoxyribonucleotide
PDRN helps repair tissue and improve wound healing with a high safety profile.
research Alopecia Areata Is Characterized by Dysregulation in Systemic Type 17 and Type 2 Cytokines, Which May Contribute to Disease-Associated Psychological Morbidity
Alopecia areata involves immune system imbalances that may lead to depression and anxiety.
research Estrogens And The Hair Follicle
Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.
research In Silico Analysis of the Age-Dependent Evolution of the Transcriptome of Mouse Skin Stem Cells
The research found that the gene activity in mouse skin stem cells changes significantly as they age.
research Nitric Oxide Signal Transduction and Its Role in Skin Sensitization
Nitric oxide is important for skin functions and both helps protect against and contributes to skin inflammation and sensitization.
research Compendium of Polycystic Ovarian Syndrome and Its Relevance in Glycation and Diabetes
PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.
research Aging Skin: A Window to the Body
Skin aging reflects overall body aging and can indicate internal health conditions.
research Effect of Topical Gel Administration of Secretome Hypoxia Mesenchymal Stem Cells on IL-10 and TNF-α Gene Expression: An In Vivo Experimental Study in Male Wistar Rats with Fluconazole-Induced Alopecia
SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.
research The Rho GTPase Exchange Factor Vav2 Promotes Extensive Age-Dependent Rewiring of the Hair Follicle Stem Cell Transcriptome
Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration
Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
research Hair Follicle Stem Cells: Walking the Maze
Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
research Biocompatible Nanoparticles and Vesicular Systems in Transdermal Drug Delivery for Various Skin Diseases
Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
research The Role of Androgen and Androgen Receptor in Skin-Related Disorders
Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.
research Quantitative Single-Cell Approaches to Stem Cell Research
New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.
research Oxidative Damage Control in a Human Mini-Organ: Nrf2 Activation Protects Against Oxidative Stress-Induced Hair Growth Inhibition
Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.
research The Biology of Hair Diversity
Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.
research Minoxidil Promotes Hair Growth Through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells
Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.
research Oncogenic Senescence: A Multi-Functional Perspective
Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.