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Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Forsythiasides have multiple health benefits but may cause pseudoallergic reactions, and more research is needed.

Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.

Improved tablets lead to faster, better drug absorption for hair loss treatment.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Hydrogel microcapsules help create cells that boost hair growth.

Male mice are more susceptible to autism-like changes from valproic acid than female mice.

Melatonin may protect hair follicle cells from damage caused by a chemotherapy drug.

Tirzepatide might help manage PCOS in obese patients but needs more research to confirm safety and effectiveness.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Loss of a specific protein in skin cells causes symptoms similar to psoriasis.

AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.

Hedgehog signaling in certain cells is crucial for hair growth during wound healing.

Keeping β-catenin levels high in mammary cells disrupts their development and branching.

BB4CMU rice bran oil may help treat hair loss and gray hair.

DNA methylation likely doesn't cause different lambskin patterns in Hu sheep.