research Identification of the Key Proteins Associated With Different Hair Types in Sheep and Goats
Different proteins are linked to the varying thickness of sheep and goat hair types.
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research Effect of Prostaglandin D2 on Hair Follicle Growth and Its Impact on Hair Follicle Stem/Progenitor Cells
Blocking Prostaglandin D₂ may help treat hair loss.
research Building and Crossing the Translational Bridge: 2016 Alopecia Areata Research Summit Highlights
The summit aimed to speed up finding treatments for alopecia areata.
research Oncostatin M Is Upstream of JAK-STAT Signaling During the Murine Hair Cycle
Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.
research Effect of Lithocholic Acid as a Ligand of Vitamin D Receptor on Hair Growth in Alopecia
Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.
research Signaling Networks Between Stem Cell Precursors, Transit Amplifying Progenitors, and Their Niche in Developing Hair Follicles
Blocking Prostaglandin D₂ (PGD₂) could help treat hair loss.
research Anti-Aging Potential of Gypenosides Fraction Obtained from Naturally Grown Gynostemma Pentaphyllum in Ulleungdo Island and Its Seven New Gypenosides
Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.
research 702 dsRNA Induces Ectopic KRT9 Expression via WNT/β-Catenin-Mediated Signaling
Double-stranded RNA activates a pathway that causes a skin protein to be expressed in the wrong place.
research RBPJ Mutations Identified in Two Families Affected by Adams-Oliver Syndrome
Mutations in the RBPJ gene cause Adams-Oliver Syndrome.
research The Genetics Of Alopecia Areata: New Approaches, New Findings, New Treatments
New genetic discoveries may lead to better treatments for alopecia areata.
research Construction of the Coexpression Network Involved in the Pathogenesis of Thyroid Eye Disease via Bioinformatics Analysis
Key genes and pathways involved in thyroid eye disease were identified, aiding potential treatment and diagnosis.
research Resequencing and Signatures of Selective Scans Point to Candidate Genetic Variants for Hair Length Traits in Long-Haired and Normal-Haired Tianzhu White Yak
The research found specific genes that may cause longer hair in Tianzhu White Yak.
research Drivers of Plateau Adaptability in Cashmere Goats Revealed by Genomic and Transcriptomic Analyses
The study found that genetic differences related to hair growth and other traits help cashmere goats adapt to high-altitude environments.
research A Missense Mutation in Lama3 Causes Androgen Alopecia
A gene mutation in Lama3 is linked to a common type of hair loss.
research Thyroid Diseases and Skin Autoimmunity
Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Generation of Tβ4 Knock-In Cashmere Goat Using CRISPR/Cas9
Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.
research Diverse Cellular Players Orchestrate Regeneration After Wounding
Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
research Wound Healing Mechanism in Mongolian Gerbil Skin
Mongolian gerbils heal wounds differently than mice, with unique protein levels and gene expression that affect skin repair.
research Combinatorial Expression of Cell Cycle Regulators Is More Suitable for Immortalization Than Oncogenic Methods in Dermal Papilla Cells
Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.
research Hair Follicle Transcriptome Profiles During the Transition from Anagen to Catagen in Cashmere Goat (Capra Hircus)
The transition from growth to regression in Cashmere goat hair follicles involves changes in expression of genes related to keratin and cell differentiation.
research Skin Organoids: A New Human Model for Developmental and Translational Research
Skin organoids are a promising new model for studying human skin development and testing treatments.
research Defining the Identity of Mouse Embryonic Dermal Fibroblasts
Researchers identified specific genes that are important for mouse skin cell development and healing.
research Mapping Human Skin: One Sequenced Cell at a Time
The article concludes that creating a detailed map of normal human skin at the single-cell level is important.
research Novel Compound Heterozygous Variants in the CDC6 Gene in a Russian Patient with Meier-Gorlin Syndrome
A young Russian girl with Meier-Gorlin syndrome has two new mutations in the CDC6 gene.
research CGF Therapy: Bridging Androgenetic Alopecia Observations to Psoriasis Treatment via IL-17 Pathway
CGF therapy may effectively treat psoriasis by reducing inflammation.
research Mouse Models for the Study of Human Hair Loss
Mice are useful for researching human hair loss and testing treatments, despite some differences between species.
research The Genetics of Human Skin Disease
Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
research NF-κB in Biology and Targeted Therapy: New Insights and Translational Implications
NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
research Type A Insulin Resistance Syndrome Due to a Novel Heterozygous c.3486_3503del (p. Arg1163_Ala1168del) INSR Gene Mutation in an Adolescent Girl and Her Mother
A new gene mutation causes insulin resistance in a girl and her mother.