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AP-2α and AP-2β are crucial for healthy skin and hair.

Some hair loss disorders cause permanent loss due to scarring, and treatments like steroids don't always work well.

The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.

Topical tacrolimus did not regrow hair in alopecia universalis patients.

The poem ends by asking for case reports on serious health issues like Telogen Effluvium.

Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.

Antimicrobial therapy can help manage Folliculitis Decalvans.

Elastin staining helps assess late-stage scarring alopecia but is not definitive, and clinical diagnosis is still crucial.

Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.

The conclusion is that primary scarring alopecia is a complex condition that requires early and accurate diagnosis for effective treatment.

A man developed a rare scalp disorder, Folliculitis Decalvans, 20 years after hair restoration surgery, and it required long-term antibiotic treatment.

Fat tissue transplant may be an effective new treatment for severe, treatment-resistant hair loss from folliculitis decalvans.

Norman Orentreich pioneered hair transplantation, improving techniques over time for more natural results.

The document corrects a name misspelling, acknowledges a pioneer in hair transplantation, and notes a missing conflict of interest disclosure.

A 90-year-old woman's hand lesion was a rare, aggressive skin cancer treated successfully with surgery.

A 5-year-old girl with a rare skin disorder was effectively treated with skin creams instead of oral medication.

A 16-year-old girl's skin rash was likely caused by an infection and improved with topical steroids.

The document corrects a missing conflict of interest and acknowledges a pioneer in hair transplantation and his other contributions.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

The conclusion is that certain scalp tissue changes are characteristic of lichen planopilaris, with mucinous perifollicular fibroplasia being a new feature for diagnosis.

Early onset and pustules indicate severe hair follicle inflammation, and while antibiotics help, the condition often worsens after treatment stops.

Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.

Some skin conditions look like acne but are caused by drugs, and they usually get better when the drug is stopped.

Some treatments for folliculitis decalvans work well, with tetracyclines and a mix of rifampicin and clindamycin being most effective.

Loss of sebaceous glands and inflammation may contribute to the development of scarring alopecia.

Long-term fluticasone treatment does not harm the immune system in horses with heaves.

Topical 0.1% tacrolimus significantly improved ear infections in cats.

Hair transplantation may work for some types of scarring alopecia, but results vary and more research is needed.

The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.

Baricitinib helped a woman with severe hair loss regrow almost all her hair without side effects.