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Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Most people with systemic lupus erythematosus have skin problems, and skin symptoms are often the first sign of the disease.

Laser device increases hair density, safe for treating hair loss in men and women.

Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.

Cathepsin L is essential for normal hair growth and development.

Generalized pustular psoriasis patients often need strong medication and careful treatment due to flare-ups and complications.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Taking selenium supplements during chemotherapy may help reduce side effects and improve health markers in ovarian cancer patients.

Skin problems are very common in people with systemic lupus erythematosus and important for diagnosis.

Oxidative stress contributes to hair graying and loss as we age.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.