research Gastrointestinal Polyposis with Protein-Losing Enteropathy, Abnormal Skin Pigmentation, and Loss of Hair and Nails (Cronkhite-Canada Syndrome)
Cronkhite-Canada Syndrome often leads to death within 6-18 months.
Search
for
Sort by
Research
780-810 / 1000+ results 
research Integrated Safety Analysis of Baricitinib in Adults With Severe Alopecia Areata From Two Randomized Clinical Trials
Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.
research A Review of Hedgehog Inhibitors Sonidegib and Vismodegib for Treatment of Advanced Basal Cell Carcinoma
Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.
research Analysis of Hidradenitis Suppurativa-Linked Mutations in Four Genes and the Effects of PSEN1-P242LfsX11 on Cytokine and Chemokine Expression in Macrophages
The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.
research Dermatological Manifestations Associated with COVID-19: A Comprehensive Review of the Current Knowledge
COVID-19 can cause various skin issues, including rashes and hair loss, which usually heal on their own and don't always indicate severe illness.
research Deoxycholic Acid in Submental Fat Reduction: A Review of Properties, Adverse Effects, and Complications
Deoxycholic acid is effective for reducing chin fat but can cause side effects and serious complications, so careful patient evaluation is needed.
research Intralesional Therapy for the Treatment of Keratoacanthoma
Intralesional therapy for keratoacanthoma is effective and has fewer side effects than systemic treatments.
research Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity
The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
research Cutaneous Toxicities of New Treatments for Melanoma
New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.
research Effects of Imiquimod on Hair Follicle Stem Cells and Hair Cycle Progression
Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.
research Regulation Mechanisms of Hair Growth
Hair regrowth slows with age and can be affected by treatments that change enzyme activity in the skin.
research Stem Cells and Aberrant Signaling of Molecular Systems in Skin Aging
Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
research Helicobacter Pylori Infection and Skin Disorders
Some skin disorders might be linked to H. pylori infection, but more research is needed to confirm this.
research Guidelines for the Use of Acitretin in Psoriasis
Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.
research Methotrexate for Generalized Pustular Psoriasis in a 2-Year-Old Child
Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.
research Genetic Fate-Mapping Reveals Surface Accumulation But Not Deep Organ Invasion of Pleural and Peritoneal Cavity Macrophages Following Injury
Cavity macrophages gather on organ surfaces but don't really invade or help repair the organs after injury.
research Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and SCD1 and SOAT1 Activity
Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.
research Friends Turned Foes: Angiogenic Growth Factors Beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research The Therapeutic Potential of CRTH2/DP2 Beyond Allergy and Asthma
CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.
research Hair Keratin KRT81 Is Expressed in Normal and Breast Cancer Cells and Contributes to Their Invasiveness
The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.
research Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair
The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.
research Bendamustine in Indolent Non-Hodgkin's Lymphoma: A Practice Guide for Patient Management
Bendamustine combined with rituximab is an effective and well-tolerated treatment for certain types of lymphoma.
research Retinoid-Mediated Stimulation of Steroid Sulfatase Activity in Myeloid Leukemic Cell Lines Requires RARα and RXR and Involves the Phosphoinositide 3-Kinase and ERK-MAP Kinase Pathways
Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
research Comparative Transcriptomic Analysis of Dermal Wound Healing Reveals De Novo Skeletal Muscle Regeneration in Acomys Cahirinus
The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.
research Thyroid Diseases and Skin Autoimmunity
Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
research Effects of Non-Ablative Fractional Erbium Glass Laser Treatment on Gene Regulation in Human Three-Dimensional Skin Models
Erbium glass laser treatment may help with skin remodeling, reduce inflammation, and improve skin cell maturation.
research Evidence of Increased DNA Methylation of the Androgen Receptor Gene in Occipital Hair Follicles from Men with Androgenetic Alopecia
Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.
research Physiological Changes and Dermatoses of Pregnancy
Most pregnant women experience skin changes like darkening and itching, while serious skin conditions are rare but need early treatment.
research Nutrition and the Deleterious Side Effects of Nutritional Supplements
Taking too many vitamin and mineral supplements can cause serious health problems.
research Safety Concerns When Using Novel Medications to Treat Alopecia
Consider benefits and risks of new alopecia treatments for safety.