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Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.

LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.

Nanomaterials show promise in improving wound healing but require more research on their potential toxicity.

IL-3 worsens lupus nephritis and blocking it improves kidney health.

Adipokines affect skin health and could be targeted for treating skin diseases.

MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.

The drug combination was safe and showed promise in treating advanced tumors.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

New targeted immunotherapies are improving treatment for inflammatory skin diseases.

Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.

Patients with RASopathies are at risk for autoimmune disorders and should be routinely screened.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.

Gloriosa superba poisoning can mimic severe tropical infections and cause rapid hair loss.

Blocking certain immune signals can reduce skin damage from radiation therapy.

Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.

Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.

Autophagy helps keep skin healthy and may improve treatments for skin diseases.

Tiny particles called extracellular vesicles show promise for skin improvement and anti-aging in facial care but face challenges like low production and lack of research.

High DHA levels delay wound healing and worsen skin repair quality.

FGF21 can help reduce skin inflammation caused by C. acnes.

UV light helped human hair transplants survive in mice without broad immunosuppression.

Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.

Povidone iodine reduced skin bacteria more than chlorhexidine gluconate, but neither met FDA reduction standards.

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

Autologous Platelet and Extracellular Vesicle-Rich Plasma (PVRP) has potential in enhancing tissue regeneration and improving hair conditions, but its effectiveness varies due to individual differences.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.