research Cyclophosphamide and Rituximab in Frequently Relapsing/Steroid-Dependent Nephrotic Syndrome
Rituximab leads to longer remission and fewer side effects than cyclophosphamide.
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research Oral Tofacitinib: A Promising Treatment in Atopic Dermatitis, Alopecia Areata, and Vitiligo
Oral tofacitinib shows promise in treating atopic dermatitis and alopecia areata, but only slight improvement in vitiligo.
research First-Line Therapy with Gemcitabine and Paclitaxel in Locally Recurrent or Metastatic Breast Cancer: A Phase II Study
Gemcitabine and paclitaxel are effective and safe as first-line treatment for metastatic breast cancer.
research Principles of Chemotherapy
Chemotherapy is crucial for treating gynecological cancers but requires careful management due to severe side effects.
research Chemotherapy-Induced Toxicity: A Secondary Effect Caused by Released DNA?
Chemotherapy toxicity might be reduced by using DNA neutralizing agents.
research Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer: Impact of CDK4/6 Inhibitors on the Current Treatment Paradigm
CDK4/6 inhibitors have improved treatment outcomes for certain advanced breast cancer patients.
research Drug Utilization Pattern and Adverse Drug Reactions of Chemotherapy in Pediatric Patients at Muhimbili National Hospital, Tanzania
Most pediatric cancer patients at Muhimbili National Hospital in Tanzania experienced side effects from chemotherapy, with nausea, hair loss, and low white blood cell count being the most common.
research Retiform Purpura Caused by the Use of Cocaine Adulterated with Levamisole
Cocaine possibly mixed with levamisole caused a woman's skin condition and blood issues, which improved with treatment.
research Pseudoglucagonoma Syndrome Following Frey's Surgery: A Case Report of a Rare Presentation
Improved nutrition quickly healed the patient's skin lesions.
research Efficacy and Safety of Baricitinib in Managing Severe Alopecia Areata: A 6-Month Real-World Experience
Baricitinib was effective and safe for severe hair loss treatment over 6 months.
research Treatment of Moderate-to-Severe Alopecia Areata in Adolescents With Baricitinib: A Retrospective Review of 29 Patients
Baricitinib helped most teenagers with severe hair loss regrow hair and had mild side effects.
research Abstracts from the ASA 40th Annual Meeting
HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.
research Severe Thiopurine-Induced Myelotoxicity and Hair Loss in Japanese Patients with NUDT15 Gene Variant: A Retrospective Case-Control Study
Screening for the NUDT15 gene variant can prevent severe side effects from thiopurine drugs in East-Asian people.
research Presumed Ocular Candidiasis in Drug Misusers After Intravenous Use of Oral High Dose Buprenorphine (Subutex)
Drug misuse can cause serious eye infections and other severe side effects.
research Toxicity Profile of Antibody-Drug Conjugates in Breast Cancer: Practical Considerations
ADCs can effectively treat breast cancer but may cause side effects like nausea and hair loss.
research Bilateral Non-Specific Orbital Inflammation (Orbital Pseudotumor), Posterior Scleritis, and Anterior Uveitis Associated with Hypothyroidism in a Child
Intralesional cidofovir might be a viable alternative treatment for certain conditions.
research Acquired Ocular Toxoplasmosis in Pregnancy
Surgical excision is the best treatment for SCC, but intralesional cidofovir might be a good alternative.
research Bilateral Anterior Uveitis as a Presenting Manifestation of Sarcoidosis and Syphilis
Surgical excision is the best treatment for SCC.
research Atypical Folliculitis Caused by Malassezia spp. in Immunosuppressed Patients
Some immunosuppressed patients can get unusual skin infections from Malassezia, which can be treated with antifungal medication.
research Oral Signs of Hematologic Disease
The conclusion is that different blood diseases cause specific oral symptoms and require varied treatments to manage these symptoms and improve patient health.
research Tangent Screens Are Still Useful in the Assessment of Vigabatrin-Induced Visual Field Defects
Tangent screens help detect visual field defects from vigabatrin.
research An Underrecognized Adverse Effect of Azithromycin: Agranulocytosis in a 67-Year-Old Man
Azithromycin can rarely cause a severe drop in white blood cells.
research Oculoplastic Surgery Atlas: Eyelid Disorders
Surgical excision is the best treatment for SCC, but intralesional cidofovir might be a viable alternative.
research Multicentric Parallel Phase II Trial of the Polo-Like Kinase 1 Inhibitor BI 2536 in Patients With Advanced Head and Neck Cancer, Breast Cancer, Ovarian Cancer, Soft Tissue Sarcoma, and Melanoma. The First Protocol of the European Organization for Research and Treatment of Cancer Network of Core Institutes
BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.
research Chemotherapy for Children with Medulloblastoma
Chemotherapy may help with survival in children with medulloblastoma, but more research is needed.
research Gemcitabine Combined With Either Pemetrexed Or Paclitaxel In The Treatment Of Advanced Non-Small Cell Lung Cancer
Combining gemcitabine with paclitaxel is more effective than with pemetrexed for advanced lung cancer.
research Use of a Healthcare Claims Database for Post-Marketing Safety Assessments of Eribulin in Japan: A Comparative Assessment with a Prospective Post-Marketing Surveillance Study
Healthcare claims databases can help monitor drug safety, but may report adverse events differently than direct surveillance.
research Innovative Sequence of Docetaxel–Gemcitabine Based on Preclinical Data in the Treatment of Advanced Non-Small Cell Lung Cancer: A Phase I Study
The new chemotherapy combination for advanced lung cancer showed a 35.7% response rate but caused significant side effects.
research Three Cases of Hemodialysis Patients with Advanced Gastric Cancer Treated with Paclitaxel and Nab-Paclitaxel
Paclitaxel and nab-paclitaxel can be safe and effective for advanced gastric cancer patients on hemodialysis.
research Dermatological Drugs, Topical Agents, And Cosmetics
The document concluded that various dermatological treatments have different effectiveness and side effects, with some causing irritation, allergic reactions, or systemic effects.