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270-292 / 292 results![Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System](/images/research/044abf40-8278-46c6-86d8-34c61d13ce0c/small/17062.jpg)
research Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System
Testosterone and its metabolites affect brain functions and could help treat neurological disorders.
research Antioxidant and Antiproliferative Activity of Finasteride against Glioblastoma Cells
![Cinnamic acid promotes elongation of hair peg-like sprouting in hair follicle organoids via oxytocin receptor activation](/images/research/e9fd5f91-1430-423f-a54e-d781ab6392a7/small/26488.jpg)
research Cinnamic acid promotes elongation of hair peg-like sprouting in hair follicle organoids via oxytocin receptor activation
Cinnamic acid may help hair grow by activating oxytocin receptors.
research Locally Synthetized 17-β-Estradiol Reverses Amyloid-β-42-Induced Hippocampal Long-Term Potentiation Deficits
A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.
![POST-FINASTERIDE SYNDROME AND POST-SSRI SEXUAL DYSFUNCTION: TWO CLINICAL CONDITIONS APPARENTLY DISTANT, BUT VERY CLOSE](/images/research/a05a9823-16b4-4fd2-a581-0330b9b75f22/small/16419.jpg)
research POST-FINASTERIDE SYNDROME AND POST-SSRI SEXUAL DYSFUNCTION: TWO CLINICAL CONDITIONS APPARENTLY DISTANT, BUT VERY CLOSE
Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.
![5α-Reductases in Human Physiology: An Unfolding Story](/images/research/746bae71-c929-4ff5-a2d7-142ec295d02c/small/14697.jpg)
research 5α-Reductases in Human Physiology: An Unfolding Story
Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.
![Analysis of the finasteride treatment and its withdrawal in the rat hypothalamus and hippocampus at whole-transcriptome level](/images/research/cde6b41f-f22f-47cb-ad63-55e8cab20c29/small/26623.jpg)
research Analysis of the finasteride treatment and its withdrawal in the rat hypothalamus and hippocampus at whole-transcriptome level
Finasteride treatment in rats changed the expression of genes related to psychiatric and neurological functions, and these changes persisted after stopping the drug.
![Androgenetic alopecia: An update](/images/research/a3f2a676-65df-47b7-b34a-42363e6d8ed2/small/15660.jpg)
research Androgenetic alopecia: An update
Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.
![Beliefs and counseling practices among dermatologists regarding sexual and other adverse effects of finasteride](/images/research/08cd96fc-eb31-42d2-b72c-fa2257e86cf3/small/31725.jpg)
research Beliefs and counseling practices among dermatologists regarding sexual and other adverse effects of finasteride
Many dermatologists believe finasteride can cause sexual side effects and counsel patients about them.
![5-alpha reductase inhibitors use in prostatic disease and beyond](/images/research/1d15248c-136b-4567-b9e1-418b115f11f5/small/12916.jpg)
research 5-alpha reductase inhibitors use in prostatic disease and beyond
5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.
research Investigation of hub genes and immune infiltration in androgenetic alopecia using bioinformatics analysis
research Gut Inflammation Induced by Finasteride Withdrawal: Therapeutic Effect of Allopregnanolone in Adult Male Rats
research Finasteride
research Case report: a study of the clinical characteristics and genetic variants of post-finasteride syndrome patients
research Association of 5α-Reductase Inhibitors With Dementia, Depression, and Suicide
![Steroid sulfatase inhibitors](/images/research/52498d9d-c334-450d-93c1-65c39b5053e2/small/15381.jpg)
research Steroid sulfatase inhibitors
Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
![Efectos adversos de finasteride: mitos y realidades. Una revisión actualizada](/images/research/d7049614-a319-46ca-af62-53d3e62febaf/small/3916.jpg)
research Efectos adversos de finasteride: mitos y realidades. Una revisión actualizada
Finasteride can cause sexual dysfunction, sperm changes, and affect bone density and metabolism.
research Behavioural characterization of Vitamin D receptor knockout mice
Vitamin D receptor knockout mice have significant motor impairments but no cognitive deficits.
![Inhibition of rat α-reductases by finasteride: Evidence for isozyme differences in the mechanism of inhibition](/images/research/8bc5eab3-e581-4713-b086-dd01248ae1c0/small/2148.jpg)
research Inhibition of rat α-reductases by finasteride: Evidence for isozyme differences in the mechanism of inhibition
Finasteride effectively blocks rat enzymes, but with varying methods and strength.
![Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases](/images/research/d8ce08f7-330c-47b2-83cc-7f1f5be83619/small/14505.jpg)
research Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases
Certain drugs that block specific enzymes can help treat prostate diseases.