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5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.

5α-Reductase inhibitors may increase depression risk but not dementia or suicide.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

Female guinea pigs exposed to less allopregnanolone before birth showed more anxiety-like behavior.

Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.

DHEA improved brain function and behavior in old monkeys and had additional health benefits.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Researchers created a new method to measure brain steroids, finding higher levels of certain steroids and changes due to a drug.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

The availability of certain hormones and specific stimulation patterns affect long-term synaptic changes in the male rat brain.

Seeing trauma causes fear in mice by lowering their natural fear-reducing hormones.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

Pregnancy and nursing increase certain brain activities in rats, but these changes disappear when the babies are taken away.

Finasteride treats hair loss but may cause low libido, erectile issues, and depression.

A natural steroid in the body may protect against eye damage in glaucoma.

Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.

Gene expression differences in PFS patients suggest a potential organic cause for symptoms.

Ferulic acid can reduce seizures and depression-like behaviors in catamenial epilepsy by balancing hormones and brain enzyme activity.

Increasing TSPO in the brain reduces anxiety and depression.

Neurosteroids play a key role in controlling the brain-adrenal gland activity in pregnant sheep, both in normal and stressful situations.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Trilostane may help delay epilepsy development by increasing certain brain chemicals.

Etifoxine, an anxiety drug, can lessen brain inflammation and cognitive issues in mice, partly by increasing production of protective brain steroids.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.