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Formononetin, found in red clover, may treat hair loss with fewer side effects.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.

Natural products may help treat skin inflammation from abnormal adrenal hormones.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.

Chitrak is a medicinal plant with health benefits like fighting microbes, reducing inflammation, and promoting hair growth, but it can be toxic and needs more research.

Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.

Both estrogens and androgens are important for health in both males and females.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

Androgens can help prevent memory problems caused by apoE4.

Flutamide, dutasteride, and finasteride dissolve differently in supercritical carbon dioxide, with dutasteride dissolving the least.

Glioblastoma cells can make androgens, which might help the tumor grow.

The dodder plant has anti-inflammatory, antimicrobial properties, and may promote hair growth.

Adiantum capillus extract reduces pain and swelling in animals.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Finasteride for hair loss can cause long-lasting sexual side effects like low libido and erectile dysfunction.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Finasteride can cause sexual problems and depression in young men.