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    Glossary Neuroprotective

    substances or mechanisms that safeguard neurons from damage

    Neuroprotective refers to substances or mechanisms that help protect nerve cells (neurons) from damage, degeneration, or death. These agents can be crucial in treating or preventing neurological disorders such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis by preserving the structure and function of neurons.

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    Research 30 of 1000+

    1. TSPO activation modulates the effects of high pressure in a rat ex vivo glaucoma model Neuropharmacology · 2016 · 16 citations
    2. The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer and Depression Korean Journal of Urology · 2014 · 75 citations
    3. Finasteride-induced depression: new insights into possible pathomechanisms Journal of Cosmetic Dermatology · 2010 · 22 citations
    4. Effects of sex steroid hormones and their metabolites on neuronal injury caused by oxygen-glucose deprivation/reoxygenation in organotypic hippocampal slice cultures Steroids · 2016 · 24 citations
    5. Novel Synthetic Steroid Derivatives: Target Prediction and Biological Evaluation of Antiandrogenic Activity Current Issues in Molecular Biology · 2025
    6. New steps forward in the neuroactive steroid field The Journal of Steroid Biochemistry and Molecular Biology · 2015 · 31 citations
    7. Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites Frontiers in Neuroendocrinology · 2020 · 18 citations
    8. Effect of the 5α-reductase enzyme inhibitor dutasteride in the brain of intact and parkinsonian mice 2017 · 16 citations
    9. Palmitoylethanolamide Stimulation Induces Allopregnanolone Synthesis in C6 Cells and Primary Astrocytes: Involvement of Peroxisome-Proliferator Activated Receptor-α Journal of Neuroendocrinology · 2011 · 52 citations
    10. The gut‐microbiota‐brain axis: Focus on gut steroids Journal of Neuroendocrinology · 2024 · 8 citations
    11. Steroid plant hormones: Effects outside plant kingdom Steroids · 2014 · 46 citations
    12. TSPO ligand etifoxine attenuates LPS-induced cognitive dysfunction in mice Brain Research Bulletin · 2020 · 5 citations
    13. Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System Androgens · 2021 · 1 citations
    14. 5α-Reductases In Human Physiology: an Unfolding Story Endocrine Practice · 2012 · 44 citations
    15. 5α-Reductases in Human Physiology: An Unfolding Story Endocrine Practice · 2012
    16. Eclipta prostrata (L.) L. (Asteraceae): Ethnomedicinal Uses, Chemical Constituents, and Biological Activities Biomolecules · 2021 · 21 citations
    17. Over-expression of TSPO in the hippocampal CA1 area alleviates cognitive dysfunction caused by lipopolysaccharide in mice Brain Research · 2016 · 18 citations
    18. A Brief Review on the Phytochemical and Pharmacological Properties of Aerial Roots of Ficus bengalensis L. (Moraceae) JOURNAL OF ENVIRONMENT AND BIO-SCIENCE · 2024
    19. A review on traditional uses, phytochemistry and pharmacology of Eclipta prostrata (L.) L. Journal of Ethnopharmacology · 2019 · 46 citations
    20. Sexual dimorphism following in vitro ischemia in the response to neurosteroids and mechanisms of injury BMC Neuroscience · 2020 · 6 citations
    21. Allopregnanolone-mediated protective effects of progesterone on tributyltin-induced neuronal injury in rat hippocampal slices The Journal of Steroid Biochemistry and Molecular Biology · 2012 · 43 citations
    22. Inhibition of 5α Reductase Impairs Cognitive Performance, Alters Dendritic Morphology and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice Neuroscience · 2020 · 13 citations
    23. Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research Journal of Neuroendocrinology · 2015 · 123 citations
    24. Neuroactive Steroids and Ethanol Exposure: Relevance to Ethanol Sensitivity and Alcohol Use Disorders Risk Elsevier eBooks · 2019 · 1 citations
    25. Effect of flutamide and two novel synthetic steroids on GABA, glutamine and some oxidative stress markers in rat brain and prostate Andrologia · 2011 · 2 citations
    26. Neurosteroids, neuroactive steroids, and symptoms of affective disorders Pharmacology, Biochemistry and Behavior · 2006 · 82 citations
    27. Fadrozole and finasteride exposures modulate sex steroid- and thyroid hormone-related gene expression in Silurana (Xenopus) tropicalis early larval development General and Comparative Endocrinology · 2009 · 60 citations
    28. Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor Neurobiology of Stress · 2019 · 40 citations
    29. Repurposing steroidogenesis inhibitors for the therapy of neuropsychiatric disorders: Promises and caveats Neuropharmacology · 2018 · 10 citations
    30. Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders Current Pharmaceutical Design · 2011 · 72 citations