4 citations,
September 2015 in “JAAD case reports” Substance P may play a role in the inflammation seen in keratosis follicularis spinulosa decalvans.
July 2023 in “International journal of trichology” Cellcurin therapy with microneedling increases hair density and thickness in treating hair loss in men and women.
2 citations,
June 2016 in “Journal of Applied Biological Chemistry” Glycine soja extract stimulates hair growth and could help treat hair loss.
Rosemary oil effectively promotes hair growth in mice.
69 citations,
May 2009 in “Journal of Investigative Dermatology” Stress might contribute to hair loss in alopecia areata.
31 citations,
May 2020 in “Dermatologic Therapy” Quarantine stress likely worsened hair loss in women, but video consultations helped manage their condition and reduce anxiety.
4 citations,
May 2014 in “Pharmaceutical Biology” The study investigated the epilatory effects of glycyrrhizic acid, a compound from sweet licorice, on hair removal in Wistar rats. A solution containing 15% glycyrrhizic acid was applied to the rats' necks twice daily, resulting in 20-30% hair loss after 3 days and 90-95% after 6-12 days. Long-term treatment reduced hair regrowth by about 20%, with no signs of skin irritation. The study suggested that glycyrrhizic acid could be a potential treatment for hypertrichosis in humans, as it effectively removed hair without causing inflammation. Further research was needed to explore its effects on human hair growth and its potential mechanisms, possibly involving hormone-like effects or changes in hair cuticle structure.
134 citations,
July 2020 in “Experimental dermatology” Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
15 citations,
January 2015 in “Dermatitis” Topical immunotherapy is the best treatment for severe alopecia areata.
1 citations,
June 2023 in “Reproduction” Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.
March 2023 in “Epilepsia” Trilostane may help delay epilepsy development by increasing certain brain chemicals.
Accurate diagnosis of cicatricial alopecias requires thorough scalp examination and multiple biopsy techniques.
November 2023 in “L'Endocrinologo” Women with PCOS are more likely to experience sexual dysfunction, but lifestyle changes and weight loss can improve sexual function.
October 2022 in “Frontiers in Endocrinology” New tools show that in fish, NPY increases feeding and somatostatin decreases it.
57 citations,
May 2014 in “Molecular Phylogenetics and Evolution” The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.
7 citations,
May 2020 in “Trends in molecular medicine” The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.
7 citations,
January 2022 in “Animal Reproduction” Using rodents for research shows that health problems in the womb can cause diseases later in life.
252 citations,
January 2008 in “Trends in Endocrinology and Metabolism” Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
200 citations,
October 2009 in “European journal of endocrinology” Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.
56 citations,
November 2010 in “Pigment Cell & Melanoma Research” Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
24 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
19 citations,
March 1998 in “Endocrinology” Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
6 citations,
April 2019 in “Russkij žurnal detskoj nevrologii” Some epilepsy drugs can cause reproductive and cosmetic side effects in women and affect pregnancy, but most women still have healthy babies.
December 2021 in “Signal transduction and targeted therapy” Increasing sebum production might help reduce fat and improve metabolism.
August 2020 in “Revista de chimie” Nitroglycerin ointment is now used to treat several skin conditions with fewer side effects.
November 2014 in “John Wiley & Sons, Ltd eBooks” Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.
86 citations,
May 2002 in “Journal of comparative neurology” Nerve growth in mouse skin and hair follicles happens in stages and is closely linked to hair development.
February 2024 in “Brain research bulletin” Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.
12 citations,
August 2015 in “Plastic Surgery” Botulinum toxin may help reduce skin flap damage caused by cigarette smoke.
9 citations,
August 2021 in “International journal of molecular sciences” PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.