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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.

Monoolein-alginate beads help heal wounds by controlling moisture and effectively delivering adenosine to the skin.

Using a patient's own tissue for micro-grafts may effectively treat non-healing leg ulcers and relieve pain.

Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.

PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.

Negative expectations can cause adverse effects in dermatology treatments, like with finasteride for baldness, and careful communication can help reduce these nocebo responses.

Some men taking finasteride for hair loss may experience sexual problems like erectile dysfunction and decreased sex drive, which can persist even after stopping the medication.

Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.

Certain spices may help prevent and treat skin cancer, but more human trials are needed.

The study found no link between anxiety, vitamin B12, folate, TSH, ferritin, zinc levels, and trichodynia in telogen alopecia patients.

A cat's hyperactivity and hair loss were caused by eating valproic acid but improved after stopping access to the drug.

The document concludes that better understanding the wound microbiome can improve chronic wound care by preserving helpful bacteria and targeting harmful ones.

Exosomes from umbilical cord cells fix hearing loss and damaged ear hair cells in mice.

Healthcare claims databases can help monitor drug safety, but may report adverse events differently than direct surveillance.

Effective symptom management in IBD improves quality of life and prevents complications.

H-1 antihistamines may help with various skin conditions, but more research is needed to confirm their effectiveness.

Poor sleep during the pandemic may increase stress and worsen hair loss conditions.

A wearable cap-like device using light therapy reduced scalp skin lesions by 71% and was painless.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

Thermography matched the patient's pain levels in a shingles case and might help diagnose shingles without a rash.

Electrospun scaffolds can improve healing in diabetic wounds.

Low-level laser therapy did not reduce licking or improve lesions in dogs with ALD but did increase hair growth.

Rapamycin may help treat Leigh syndrome by targeting protein kinase C.

Biodegradable microneedle patches help topical steroids work better for prurigo nodularis.

Skin symptoms without a medical cause often reflect psychological stress and are influenced by culture, requiring a team approach for treatment.

Platelet-rich plasma may improve healing and hair growth in cosmetic surgery but results vary.

Mild exercise reduces pain in older rats through a brain chemical, while intense exercise reduces pain in all rats through a different pain-blocking process.

Hormone imbalances from endocrine diseases can cause various skin conditions that help diagnose and treat these diseases early.

The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.