research Hormone-Dependent Medial Preoptic, Lumbar Spinal Cord, and Autonomic Coordination Supporting Male Sexual Behaviors
Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.
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research Comparative Transcriptomic Analysis of Human Mesenchymal Stem Cells Derived from Dental Pulp and Adipose Tissues
Dental pulp stem cells are better for tissue repair, while fat tissue stem cells may be more suited for wound healing and hair growth.
research Biologics in the Management of Childhood Atopic Dermatitis
Biologics, especially Dupilumab, are effective and safe for treating severe childhood eczema.
research Antiepileptogenic Effects of Trilostane in the Kainic Acid Model of Temporal Lobe Epilepsy
Trilostane may help delay epilepsy development by increasing certain brain chemicals.
research Mice With a Null Mutation of the TGFα Gene Have Abnormal Skin Architecture, Wavy Hair, and Curly Whiskers and Often Develop Corneal Inflammation
TGFα gene mutation in mice causes abnormal skin, wavy hair, curly whiskers, and sometimes eye inflammation.
research A Subpopulation of Itch-Sensing Neurons Marked by Ret and Somatostatin Expression
Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
research Neurosteroid-Sensitive δ-GABAA Receptors: A Role in Epileptogenesis?
Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.
research Exploring the Impact of the Microbiome on Neuroactive Steroid Levels in Germ-Free Animals
Gut microbes significantly affect brain steroid levels.
research Sensory Reinnervation of Human Skin by Human Neural Stem Cell-Derived Peripheral Neurons Ex Vivo
Human skin can be reconnected to nerves using stem cells, which may help with skin health and healing.
research Episodic Bilateral Corneal Edema Caused by Hair Grooming Gel
research Hydrophilic Melanin as a Potential Hair Growth Stimulant: A Secondary Observational Study
Hydrophilic melanin may help hair grow by improving blood flow and regeneration.
research Tackling Underrepresentation to Aid Understanding of Parkinson’s Disease: Progress and Further Opportunities
Increasing research diversity is key for better understanding and treating Parkinson's Disease.
research Cell Death by Cornification
Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
research The Stem Cell Niche in Regenerative Medicine
Targeting and modifying the stem cell niche can improve regenerative therapies.
research Targeting Smoothened for Therapeutic Gain
Targeting the Smoothened receptor shows promise for treating certain cancers.
research Dynamic Regulation of Retinoic Acid-Binding Proteins in Developing, Adult, and Neoplastic Skin Reveals Roles for β-Catenin and Notch Signaling
Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.
research Cluster Headache: Acute and Prophylactic Therapy
Sumatriptan injections, high-flow oxygen, and verapamil effectively treat cluster headaches.
research The Itchy Scalp: Scratching for an Explanation
Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.
research Androgens and Ovarian Function: Translation from Basic Discovery Research to Clinical Impact
Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
research Functional Enhancers as Master Regulators of Tissue-Specific Gene Regulation and Cancer Development
Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.
research Odontogenic Keratocysts Arise from Quiescent Epithelial Rests and Are Associated with Deregulated Hedgehog Signaling in Mice and Humans
Odontogenic keratocysts are caused by abnormal Hedgehog signaling and can lead to tooth and bone issues.
research CRF Receptor Antagonist Astressin-B Reverses and Prevents Alopecia in CRF Over-Expressing Mice
Astressin-B can reverse and prevent hair loss in stressed mice.
research BMP2-Mediated PTEN Enhancement Promotes Differentiation of Hair Follicle Stem Cells by Inducing Autophagy
BMP2 helps hair follicle stem cells become specialized by increasing PTEN, which causes autophagy.
research Marine Health-Promoting Compounds: Recent Trends for Their Characterization and Human Applications
Seaweeds contain beneficial compounds with potential uses in food, cosmetics, and health, but more research is needed to improve extraction and safety.
research Toxicology and Pharmacology of Botulinum and Tetanus Neurotoxins: An Update
Botulinum and tetanus neurotoxins are better understood now, with updated information on their effects and treatment.
research Immunopathology and Immunotherapy of Inflammatory Skin Diseases
New targeted immunotherapies are improving treatment for inflammatory skin diseases.
research Iron Deficiency in Menstruating Adult Women: Much More Than Anemia
Iron deficiency in menstruating women causes many health issues beyond anemia and needs early detection and treatment.
research Tissue-Selective Regulation of Androgen-Responsive Genes
The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.
research Gene-Knockout Mice With Abnormal Epidermal and Hair Follicular Development
Knocking out certain genes in mice helps understand skin and hair growth problems.
research Editorial: Mesenchymal Stromal Cell Therapy for Regenerative Medicine
Mesenchymal stromal cell therapies show promise for treating various diseases but need more research and standardization.