research Cleave But Not Leave: Astrotactin Proteins in Development and Disease
Astrotactin proteins are important for brain and skin development and are linked to several neurodevelopmental disorders.
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240-270 / 1000+ results research Mitochondrial Dysfunction in an Animal Model of Diabetic Neuropathy Is Associated with a Reduction of Neurosteroid Synthesis
Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.
research Self-Assembled Peptide Hydrogels in Regenerative Medicine
Peptide hydrogels show promise for healing skin, bone, and nerves but need improvement in stability and compatibility.
research Spatiotemporal Dynamics of Sensory Neuron and Merkel-Cell Remodeling During Epidermal Homeostasis
Sensory neurons and Merkel cells remodel at different rates during normal skin maintenance.
research Unravelling a Novel Role for Cannabidivarin in the Modulation of Subventricular Zone Postnatal Neurogenesis
Cannabidivarin (CBDV) helps new brain cells grow and develop in a specific brain area through a certain receptor.
research Administration of Dutasteride in Animal Models of Retinitis Pigmentosa
Dutasteride potentially improves cell survival and reduces retinal damage in retinitis pigmentosa.
research Follicle-Innervating Aδ-Low Threshold Mechanoreceptors Organize Through a Population-Dependent Mechanism
Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.
research 4-Aminopyridine Promotes Accelerated Skin Wound Healing via Neurogenic-Mediator Expression
4-aminopyridine, a FDA-approved drug, speeds up skin wound healing and tissue regeneration.
research Decision Letter: Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
research Optogenetically Controlled TrkA Activity Improves the Regenerative Capacity of Hair-Follicle-Derived Stem Cells to Differentiate into Neurons and Glia
Blue-light activation of TrkA improves hair-follicle stem cells' ability to become neurons and glial cells.
research Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research
New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
research Isotope Dilution-Based Targeted and Nontargeted Carbonyl Neurosteroid/Steroid Profiling
Researchers created a new method to measure brain steroids, finding higher levels of certain steroids and changes due to a drug.
research Highly Efficient Neural Differentiation of CD34-Positive Hair-Follicle-Associated Pluripotent Stem Cells Induced by Retinoic Acid and Serum-Free Medium
Hair follicle stem cells can become nerve cells using specific treatments.
research Zinc Deficiency Triggers Hearing Loss by Reducing Ribbon Synapses of Inner Hair Cells in CBA/N Mice
Lack of zinc can cause hearing loss by damaging important parts of inner ear cells in mice.
research A Preview of Selected Articles on DNA Methylation and mTOR Signaling Pathways in Stem Cell Function and Differentiation
The document concludes that DNA methylation and the mTOR pathway are important for stem cell function and could impact disease treatment.
research The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons
Different hair follicles in the skin are innervated by unique combinations of mechanosensory neurons, crucial for touch sensation.
research Membrane Androgen Receptors May Mediate Androgen Reinforcement
Androgen self-administration might be controlled by membrane receptors, not nuclear ones.
research Finasteride Treatment Inhibits Adult Hippocampal Neurogenesis in Male Mice
Finasteride reduces new brain cells in male mice, possibly causing depression.
research MiR-124 Promotes Neural Differentiation in Mouse Bulge Stem Cells by Repressing Ptbp1 and Sox9
miR-124 helps mouse hair follicle stem cells become nerve cells by blocking Ptbp1 and Sox9.
research Procyanidins Attenuate Neuropathic Pain by Suppressing Matrix Metalloproteinase-9/2
Procyanidins from grape seeds reduce nerve pain by blocking specific proteins and inflammation.
research Roles of Steroid Sulfatase in Brain and Other Tissues
Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.
research Relating Neurosteroid Modulation of Inhibitory Neurotransmission to Behavior
Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
research Lesions in the Skin, Intestine, and Central Nervous System Induced by an Antimetabolite of Niacin
Injecting newborn mice with a niacin blocker caused skin, gut, and brain damage similar to human pellagra.
research Multimodal Imaging of Hair Follicle Bulge-Derived Stem Cells in a Mouse Model of Traumatic Brain Injury
Hair follicle stem cells might help treat traumatic brain injury.
research Synchronizing Actin and Microtubules for Axonal Branching
Certain proteins help nerve cells branch, and other findings relate to cancer, stem cell behavior, and cell division.
research Trazodone By Epigenetic Mechanism Can Reverse The Post Finasteride Syndrome
Trazodone might help reverse post finasteride syndrome.
research 4-Aminopyridine Promotes Accelerated Skin Wound Healing via Neurogenic-Mediator Expression
4-aminopyridine helps skin wounds heal faster and better.
research In Vitro Co-Culture Models of Merkel Cell-Neurite Complex in Touch Domes
The study concluded that the developed models are effective for studying hair growth mechanisms and testing new treatments.
research Divergent Neuroactive Steroid Responses to Stress and Ethanol in Rat and Mouse Strains: Relevance for Human Studies
Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.
research Touch Receptors Undergo Rapid Remodeling in Healthy Skin
Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.