research Non-Apoptotic Role for Caspase-7 in Hair Follicles and Surrounding Tissue
Caspase-7 has functions in skin and hair that are not related to cell death.
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research Hair Graying Regulators Beyond Hair Follicle
Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.
research Differentiation of Nestin-Negative Human Hair Follicle Outer Root Sheath Cells Into Neurons In Vitro
Human hair follicle cells can be turned into neural stem cell-like cells, which might help treat brain diseases.
research Function of KLF4 in Stem Cell Biology
KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
research A 5α-Reductase Inhibitor, Finasteride, Increases Differentiation and Proliferation of Embryonal Carcinoma Cell-Derived Neural Cells
research A Microscopy-Based Small Molecule Screen in Primary Neurons Reveals Neuroprotective Properties of the FDA-Approved Anti-Viral Drug Elvitegravir
The anti-viral drug Elvitegravir may protect brain cells from damage related to neurodegenerative diseases.
research A Review of the Role of Psychiatrists and Pediatricians in Outpatient Treatment of Adolescents with Anorexia and Bulimia Nervosa
Family-based treatment is the best outpatient care for stable teens with anorexia, and more research is needed on medication and treatment effectiveness for young people with eating disorders.
research Can Male-Pattern Baldness Be Prevented? Promising Results from a Study on Treating Male-Pattern Baldness with Oral Finasteride
Finasteride may increase hair growth and prevent baldness in men, but can cause sexual side effects.
research Early Postnatal Allopregnanolone Levels Alteration and Adult Behavioral Disruption in Rats: Implications for Drug Abuse
Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.
research Tissue Homeostasis and Regeneration: Human Limitations and Potential
Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.
research Drug Repurposing in Dermatology: Molecular Biology and Omics Approach
Old drugs like finasteride and spironolactone are being successfully used for hair loss and skin conditions, and many other drugs show promise for new uses in dermatology.
research Global Landscapes of Human Phenotypic Variation in Inherited Traits
Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.
research Analysis of Androgen Receptor Expression and Activity in the Mouse Brain
Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.
research A Review and Brief Explanation of Polycystic Ovarian Syndrome
PCOS affects many women and requires early detection and symptom management.
research Topical Sodium Valproate-Loaded Nanospanlastics Versus Conventional Topical Steroid Therapy in Alopecia Areata: A Randomized Controlled Study
Both treatments for alopecia areata showed similar modest effectiveness.
research Application of Metal Organic Frameworks-Based Functional Composite Scaffolds in Tissue Engineering
Metal organic frameworks-based scaffolds show promise for tissue repair due to their unique properties.
research Incidence of Cicatricial Alopecia Among New Alopecia Patients Undergoing Platelet-Rich Plasma
6.1% of patients seeking PRP for hair loss had undiagnosed cicatricial alopecia, which PRP cannot treat.
research Application of an Artificial Intelligence Photographic Device to Track Platelet-Rich Plasma Treatment Outcomes in Females with Alopecia
An AI photographic device effectively tracked hair growth improvements in women treated for hair loss.
research When Acne, Hirsutism, and Menstrual Irregularities Are More Than PCOS
Non-classic congenital adrenal hyperplasia (NCCAH) can mimic PCOS and requires genetic testing for proper diagnosis and treatment.
research Murine Sebaceous Gland Homeostasis Requires Intact Cutaneous Innervation in a Hair Cycle-Dependent Context
Mouse skin glands need healthy nerves to grow properly during hair growth phases.
research Hair Follicles Employ a Two-Dimensional Healing Strategy to Repair Three-Dimensional Injuries
Hair follicles repair 3D injuries using a 2D healing process.
research Non-Coding Double Stranded RNA Induces Retinoic Acid Synthesis and Retinoid Signaling to Control Regeneration
Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.
research First Reboxetine Trial Results Reported
Finasteride increased hair count and regrowth in men with hair loss but also caused more sexual side effects than placebo.
research News in Brief
A new protein linked to Alzheimer's was discovered, and a hair loss treatment showed effectiveness but had some sexual side effects.
research MicroRNA Control of Signal Transduction
MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.
research Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
research Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance
Understanding phenotypic plasticity is crucial for developing effective cancer therapies.
research Minoxidil: Mechanisms of Action on Hair Growth
Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
research Potential Role and Therapeutic Interests of Myo-Inositol in Metabolic Diseases
Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.
research Regulation of Somatic Cell Reprogramming Through Inducible miR-302 Expression
Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.