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Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The Rotterdam Study aims to understand various diseases in older adults.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Stem cell niches support, regulate, and coordinate stem cell functions.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Stem cell self-renewal is complex and needs more research for full understanding.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.