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Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.

BMP signaling is essential for the development of touch domes.

A pregnant woman's skin condition improved after giving birth, possibly due to high estrogen levels during pregnancy.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Trichotillomania is more common than previously thought, with increasing diagnosed cases.

Melatonin directly affects mouse hair follicles and may influence hair growth.

The document concludes that surgery is a preferred treatment for cicatricial alopecia, with the method chosen based on individual factors and may require multiple sessions and careful postoperative care.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

Chronic scalp pain in trichodynia involves both body-wide and localized increased pain sensitivity.

George Ernest Rogers was a notable scientist who made important discoveries about hair and wool proteins.

A woman with anorexia and Cushing's syndrome improved after tumor removal, highlighting the need to consider hormonal issues in psychiatric conditions.

A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.

Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.

Thallium, mercury, selenium, and colchicine strongly cause hair loss.

Different amounts of daylight affect cashmere growth in goats by changing the activity of certain genes and molecules.

Alisertib was found to be an effective and tolerable treatment for children with recurrent brain tumors.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

Transfollicular drug delivery is promising but needs more research to improve and understand it better.

Air Vice-Marshal Sir Ralph Jackson significantly advanced dialysis technology in the UK.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Genetic variants in PDE6H and LPAR6 cause vision impairment and hair loss in two Pakistani brothers.

Celiac disease can cause skin problems that may get better with a gluten-free diet.

Gray hair can potentially be reversed, leading to new treatments.

Hair transplantation in East Asians needs special techniques to ensure natural results and prevent complications due to their unique hair and scalp characteristics.

The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.

A woman with a unique syndrome similar to TRPS has a genetic change near the TRPS1 gene, affecting its regulation.

The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.