research Localization of Members of the Notch System and the Differentiation of Vibrissa Hair Follicles: Receptors, Ligands, and Fringe Modulators
Notch-related genes play a key role in the development and cycling of hair follicles.
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research Small Molecules and Small Molecule Drugs in Regenerative Medicine
Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
research Deciphering the Mesodermal Potency of Porcine Skin-Derived Progenitors by Microarray Analysis
Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
research Lineage Potential, Plasticity, and Environmental Reprogramming of Epithelial Stem/Progenitor Cells
Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.
research Tissue Homeostasis and Regeneration: Human Limitations and Potential
Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.
research Use of Oral Isotretinoin in the Treatment of Frontal Fibrosing Alopecia: Case Series
Oral isotretinoína effectively stabilizes frontal fibrosing alopecia.
research Molecular Mechanisms of Type II Spiral Ganglion Neuron Development
research PRC2 Preserves Intestinal Progenitors and Restricts Secretory Lineage Commitment
PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.
research SOX9 in Organogenesis: Shared and Unique Transcriptional Functions
SOX9 is essential for the development of various organs and hair follicles.
research Nephrogenic Systemic Fibrosis: Report of Two Cases
The document concludes that using gadolinium-based contrast agents during MRI can be linked to Nephrogenic Systemic Fibrosis in patients with severe kidney disease.
research The Successful Treatment of Nephrogenic Fibrosing Dermopathy with Mycophenolate Mofetil
Mycophenolate mofetil improved skin condition in a man with nephrogenic fibrosing dermopathy.
research Nerve Dependence in Tissue, Organ, and Appendage Regeneration
Nerves are crucial for the regeneration of various body parts in many animals.
research Epithelial Stem Cells And Implications For Wound Repair
Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
research Phase I Safety and Pharmacokinetic Study of SU-014813 in Combination with Docetaxel in Patients with Advanced Solid Tumors
The drug combination was safe and showed promise in treating advanced tumors.
research An Antifungal for Antidiuresis? Fluconazole's Potential in Treating Nephrogenic Diabetes Insipidus
Fluconazole might be a new treatment for a type of diabetes that affects water balance in the body.
research Wound-Induced Hair Follicle Neogenesis as a Promising Approach for Hair Regeneration
Hair can regrow after significant damage through a process similar to how it forms before birth, involving stem cells and various cell types and signals. This could be a new way to prevent scarring and promote hair growth.
research Targeting Receptor–Regulator Interactions
New treatments for cancer and skin disorders show promise in disrupting harmful cell interactions and promoting hair growth.
research Chaperones as Thermodynamic Sensors
New cancer treatments show promise in reducing tumor growth and improving skin regeneration in mice.
research Boosting Hair Follicle Regeneration
A protein called FGF9 helps regenerate hair follicles in mice after skin damage, and increasing FGF9 could potentially help human hair growth.
research Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts During Wound Healing
Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.
research Differential Expression of Retinoic Acid-Synthesizing (RALDH) Enzymes During Fetal Development and Organ Differentiation in the Mouse
Different enzymes are active in different parts of developing mouse organs.
research Open-Label, Randomized, Multicenter, Phase III Study Comparing Oral Paclitaxel Plus Encequidar Versus Intravenous Paclitaxel in Patients With Metastatic Breast Cancer
Oral paclitaxel plus encequidar improved tumor response and caused less neuropathy but more serious infections than intravenous paclitaxel.
research Skin in Systemic Disease
Skin problems can indicate different diseases inside the body.
research Managing the Adverse Effects of Cytotoxic Chemotherapy at the Level of Primary Healthcare
Primary healthcare clinics are key in managing chemotherapy side effects using various medications and treatments.
research Research Highlights: Gamma Delta T Cells Regulate Hair Follicle Neogenesis During Adult Wound Healing
γδ T cells help with hair growth during wound healing in mice.
research Atrophying Squamous Papulous Dermatitis (Degos Disease): Nine Years of Follow-Up
A woman with Degos disease managed her condition for nine years with medications and had two healthy pregnancies, while a separate finding suggests a possible link between female pattern hair loss and high blood pressure.
research Highlights From the Literature
Apoptosis, not oxidative stress, is linked to aging in mice with mtDNA mutations.
research Blood Pressure Levels in Women with Androgenetic Alopecia
Women with androgenetic alopecia may have higher blood pressure levels.
research Is the Comb Over Dying? A Mouse Model for Male Pattern Baldness (Androgenic Alopecia)
The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.
research PI3K/Akt Signaling Pathway Is Essential for De Novo Hair Follicle Regeneration
PI3K/Akt pathway is crucial for hair growth and regeneration.