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Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

The document concludes that more research is needed to fully understand the causes of PCOS.

Dermatologists can help diagnose endocrine disorders like PCOS and metabolic syndrome by looking at skin symptoms.

Infrared radiation can cause skin aging and cancer at high temperatures but may have therapeutic benefits at controlled levels.

Beta-HPV and MCPyV are linked to certain skin cancers, with ongoing research and vaccine development.

High androgen levels in postmenopausal women may suggest an ovarian tumor, and removing it can improve heart and metabolic health.

Menopausal acne is treated with medications and lifestyle changes, but careful choice is needed due to side effects.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.

PCOS has a strong genetic basis, but more research is needed to fully understand it.

The document concludes that periocular hair disorders have various causes and treatments, and proper evaluation by specialists is important for management and prognosis.

Environmental factors can cause mutations in skin proteins, leading to skin disorders.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.

Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.

Melatonin may help manage PCOS by improving insulin sensitivity, hormone balance, and mood.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Chaga mushrooms contain compounds that may promote hair growth better than common treatments.

The document concludes that autoimmune skin disorders are treated with corticosteroids and immunosuppressive drugs.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.