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This source reviews mechanisms and existing treatments for hair aging, highlighting factors like oxidative stress and DNA repair defects that affect hair follicle and stem cell function, and discusses research limitations and future directions in the field.

In this study, researchers found that in late pregnancy, the neuroactive progesterone metabolite allopregnanolone inhibits HPA axis responses to immune challenges via an opioid-mediated mechanism.

This review discusses various therapeutic strategies targeting platelet-derived growth factor signaling in diseases like cancer and atherosclerosis, and evaluates existing treatments without presenting new clinical data.

This review discusses emerging targets for developing drugs to treat hair loss and reports no new clinical results; the authors emphasize the potential for therapies that regenerate hair follicles.

This review synthesizes recent research to propose a precision framework for treating androgenetic alopecia and alopecia areata based on genetic insights and pathway biology, highlighting the roles of androgen-receptor signaling, immune dysregulation, and emerging therapies like regenerative medicine and AI-assisted diagnostics.

This review discusses the advancements in intraoperative stem cell therapies and highlights their potential to improve hair regrowth, but it reports no new clinical results.

This study in mice demonstrated that stress or nerve growth factor injection increases sensory neuron activity related to skin innervation, suggesting a strong connection between stress perception and neurogenic skin inflammation.

This study found that psychoemotional stress disrupts hair growth in mice by terminating anagen and suggests a potential pathway for pharmacological management of stress-related hair loss in humans.

This article reviews the potential role of prolactin as a neuroendocrine modulator in skin biology and pathology, discussing its relevance for conditions such as psoriasis and hair growth, but reports no new clinical findings.

This study presents the first report on cloning and characterizing the full-length cDNA of SRD5A1 in Indian catfish (Clarias magur), revealing expression differences across reproductive phases and increased expression post-Ovatide administration in ovaries and testis.

This study used single-cell RNA sequencing to create a detailed atlas of human scalp hair follicles and found that early-stage hair graying involves matrix hair progenitor depletion linked to P53 pathway activation.

Hair graying may help prevent cancer by protecting stem cells.

This study found that only eumenorrheic polycystic ovary syndrome patients showed a temporal coupling between kisspeptin and luteinizing hormone pulsatile secretions.

This review discusses how the CRH/POMC systems may regulate human hair follicle pigmentation and highlights the concept of "self-similarity" in melanocortin systems at both local and systemic levels, without presenting new experimental results.

This study observed that in an ex vivo setting, 17β-estradiol increased CB1 expression in human hair follicles, suggesting possible sensitivity to endocannabinoids and a potential mechanism for hair therapy.

This study reviews the current understanding of psychiatric disorders in women with PCOS, finding links to the gut-brain axis, neurotransmitter and neuroendocrine dysfunction, and suggests the need for routine mental health screening in these patients.

This case study suggests that palash basti, a form of Ayurvedic treatment, may effectively manage polyendocrine metabolic ovarian syndrome by improving menstrual regularity and hormonal balance, though further studies are needed.

This review discusses the role of the TOR pathway in aging and suggests that rapamycin could potentially target age-related diseases, but reports no new clinical results.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

This review covers recent findings on stem cell plasticity under normal and cancerous conditions but presents no new experimental results, highlighting implications for regenerative medicine and cancer treatments.

This review examines the adaptive value and mechanisms of seasonal coat colour moulting in birds and mammals, highlighting the challenge of camouflage mismatch and the necessity for evolutionary adaptation under climate change.

This study found that skin-derived precursor cells in mice can originate from both neural crest and somite lineages but show functional similarities regardless of their developmental origins.

This article discusses the roles of epidermal stem cells in maintaining skin homeostasis and highlights how deregulation in signaling pathways may lead to cancer, but it reports no new experimental results.

This study found that DKK1 and WNT10b are paracrine factors that modulate hair follicle stem cell differentiation inhibition, contributing to androgenetic alopecia by affecting Wnt signaling in androgen-sensitive dermal papilla cells after dihydrotestosterone stimulation.

This review discusses Chrousos syndrome, a rare condition caused by NR 3C1 gene mutations leading to glucocorticoid resistance, and reports no new clinical results; early identification and genetic testing are recommended for diagnosis.

This review discusses lung regeneration and highlights the role of facultative stem/progenitor cells, but it reports no new findings and calls for further exploration of underlying mechanisms.

This review discusses how acute exposures to environmental and internal stressors can quickly alter skin functions, leading to various dermatological symptoms, and calls for more research on these short-term effects.

This study suggests that prolactin has complex, gender- and location-dependent effects on human hair follicles, promoting hair growth in female frontotemporal scalp areas while inhibiting it in male occipital regions.

This study found that exposure to sex steroid biosynthesis inhibitors increases the expression of piRNA pathway genes in frog larvae, suggesting these genes play a role in gonadal sex differentiation.

This review covers the neuroendocrine aspects of polycystic ovary syndrome, focusing on hormones and neurotransmitters like GnRH and kisspeptin, but does not report new clinical findings.