Search

everythinglearnresearchcommunity

for

Search:↓

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

PCOS is caused by both genetics and environmental factors like diet and obesity.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Androgens can both increase and decrease hair growth in different parts of the body.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Preoperative pain assessment, regional anesthesia, and vitamin C can help prevent CRPS after surgery.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Activating TRPV3 stops human hair growth.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.