153 citations,
November 2004 in “Current Medicinal Chemistry” The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
87 citations,
May 2012 in “PLOS Genetics” Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.
27 citations,
September 2015 in “PharmaNutrition” Astaxanthin is a safe antioxidant that may improve heart, skin, eye health, and physical performance, and help manage chronic diseases.
6 citations,
September 2019 in “Journal of cosmetic dermatology” Lower melatonin levels are linked to more skin aging.
6 citations,
October 2016 in “Food Science and Biotechnology” The water extract of Bituminaria bituminosa, high in phenolic compounds, shows strong antioxidant and enzyme inhibitory potential.
1 citations,
November 2018 in “Therapeutic Delivery” New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.
January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Semecarpus anacardium leaf extracts may offer safe, effective cancer treatment alternatives.
January 2016 in “Springer eBooks” A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.
January 2014 in “Springer eBooks” Inflammasome proteins can indicate the severity and treatment response of various diseases and injuries.
2 citations,
March 2022 in “Applied sciences” Lespedeza bicolor extract promotes hair growth and increases hair follicle cell growth, potentially making it a better treatment than minoxidil.
2 citations,
October 2022 in “Journal of Biomedical Science” Stem cells and their secretions could potentially treat stress-induced hair loss, but more human trials are needed.
17 citations,
April 2021 in “Frontiers in Pharmacology” Activating Nrf2 can help protect against hearing loss.
219 citations,
January 2006 in “Drug Metabolism Reviews” DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
60 citations,
July 2014 in “Autophagy” The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
13 citations,
January 2023 in “Frontiers in Nutrition” Lindera aggregata has many beneficial compounds that can help prevent and manage diseases.
8 citations,
September 2022 in “Human genomics” Key genes and pathways involved in thyroid eye disease were identified, aiding potential treatment and diagnosis.
4 citations,
April 2020 in “Reports of Practical Oncology & Radiotherapy” Prostate cancer patients need early psychological and sexual support during radiotherapy to improve their quality of life.
April 2023 in “Chinese Medical Journal” Human hair follicle stem cells help repair tendon injuries.
November 2019 in “Harper's Textbook of Pediatric Dermatology” Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.
59 citations,
June 2008 in “Journal of The American Academy of Dermatology” The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
19 citations,
December 2015 in “European Journal of Human Genetics” A rare ITGB6 gene variant causes intellectual disability, hair loss, and dental issues.
151 citations,
June 2010 in “Endocrinology and metabolism clinics of North America” Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.
15 citations,
October 1970 in “Archives of disease in childhood” Hair amino acid levels can indicate metabolic disorders.
7 citations,
July 2011 in “Survey of Ophthalmology” The document concludes that periocular hair disorders have various causes and treatments, and proper evaluation by specialists is important for management and prognosis.
2 citations,
September 2023 in “Cosmetics” Cannabinoids may help some skin conditions but more research is needed.
4 citations,
October 2013 in “Springer eBooks” Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.
1 citations,
February 2023 in “International Journal of Molecular Sciences” Melatonin, the sleep hormone, can help treat skin conditions like dermatitis, hyperpigmentation, and scalp disorders, and may also aid in skin aging prevention and regeneration. However, it's not recommended for asthma due to its pro-inflammatory effect.
November 2023 in “Frontiers in cell and developmental biology” Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.
142 citations,
March 2019 in “Frontiers in Cellular Neuroscience” The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
107 citations,
December 2013 in “International Journal of Dermatology” The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.