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The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Taking too many vitamin and mineral supplements can cause serious health problems.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

FoxN1 overexpression in young mice harms immune cell and skin development.

A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.

Melanocytes are important for skin and hair color and protect the skin from UV damage.

Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.

The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.

Activating β-catenin increases melanocytes and decreases Schwann cells.

The demineralized bone matrix scaffold is better for cell attachment than the mineralized bone allograft.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

BMP2 and BMP7 have opposite roles in feather formation.

Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Stem cell niches are adaptable and key for tissue maintenance and repair.

Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.