research Tissue Engineering and Regenerative Medicine: Achievements, Future, and Sustainability in Asia
Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
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research Targeting the Wnt Pathways for Therapies
Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
research Overexpression of Smad7 Results in Severe Pathological Alterations in Multiple Epithelial Tissues
Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.
research Quantitative Single-Cell Approaches to Stem Cell Research
New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.
research Prolactin and the Skin: A Dermatological Perspective on an Ancient Pleiotropic Peptide Hormone
Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.
research Protection Against Chemotherapy-Induced Alopecia
No treatment fully prevents hair loss from chemotherapy yet.
research Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin
The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
research Wnt/β-Catenin Pathway in Tissue Injury: Roles in Pathology and Therapeutic Opportunities for Regeneration
The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
research Conditioned Media Derived from Mesenchymal Stem Cell Cultures: The Next Generation for Regenerative Medicine
Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.
research Role of Cholesterol Sulfate in Epidermal Structure and Function: Lessons from X-Linked Ichthyosis
Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
research Flares of Systemic Lupus Erythematosus During Pregnancy and the Puerperium: Prevention, Diagnosis, and Management
Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.
research The Blastema and Epimorphic Regeneration in Mammals
Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
research Development and Homeostasis of the Skin Epidermis
The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
research Molecular Signaling in Feather Morphogenesis
Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.
research Epidermal Stem Cells and Skin Tissue Engineering in Hair Follicle Regeneration
Hair follicle regeneration needs special conditions and young cells.
research Diversification and Specialization of Touch Receptors in Skin
Skin has specialized touch receptors that can tell different sensations apart.
research Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells
Muscles and nerves that cause goosebumps also help control hair growth.
research Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth
Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
research Wnt Signaling in Skin Organogenesis
Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
research mTOR Signaling Promotes Stem Cell Activation via Counterbalancing BMP-Mediated Suppression During Hair Regeneration
mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.
research Electrospun Nanofibers for Improved Angiogenesis: Promises for Tissue Engineering Applications
Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.
research Drug Discovery for Alopecia: Gone Today, Hair Tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
research Molecular Basis of Hair Cell Loss
The document concludes that there are no effective clinical treatments for hearing loss due to hair cell damage, but research is ongoing.
research Hair Follicle: A Novel Source of Multipotent Stem Cells for Tissue Engineering and Regenerative Medicine
Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.
research Perspectives of Kennedy's Disease
Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.
research Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened
The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.
research Compartmentalized Organization: A Common and Required Feature of Stem Cell Niches?
Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
research The Majority of Multipotent Epidermal Stem Cells Do Not Protect Their Genome by Asymmetrical Chromosome Segregation
Most hair follicle stem cells do not protect their DNA by dividing it unevenly.
research The Genetics of Hair Shaft Disorders
The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
research Regulatory Roles of Androgens in Cutaneous Wound Healing
Testosterone may slow down wound healing and increase inflammation.