Wound healing is complex and requires more research to enhance treatment methods.
1250 citations,
August 2021 in “Scientific Reports” COVID-19 leaves 80% of patients with long-term symptoms like fatigue and headaches.
441 citations,
May 2008 in “British Journal of Pharmacology” Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
359 citations,
September 2017 in “European Journal of Epidemiology” The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
336 citations,
August 2015 in “European Journal of Epidemiology” The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
321 citations,
March 2015 in “Nature” Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.
277 citations,
July 2002 in “Molecular Endocrinology” Removing part of the vitamin D receptor stops vitamin D from working properly.
253 citations,
April 2014 in “Drugs” Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.
238 citations,
March 2013 in “Development” Fat cells help recruit healing cells and build skin structure during wound healing.
218 citations,
January 2013 in “The Lancet Oncology” Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
211 citations,
February 2009 in “European journal of pharmaceutics and biopharmaceutics” Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.
199 citations,
April 2010 in “Nature” A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
184 citations,
December 2018 in “Nature Communications” Researchers created human hair follicles using a new method that could help treat hair loss.
171 citations,
October 1990 in “Alcoholism/Alcoholism, clinical and experimental research” The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.
170 citations,
September 2019 in “Evidence-based Complementary and Alternative Medicine” Some medicinal plants can help heal wounds and may lead to new treatments.
165 citations,
September 2001 in “Genes & development” CDP is crucial for lung and hair follicle cell development.
151 citations,
February 2007 in “International Journal of Dermatology” Alopecia areata causes hair loss, has no cure, and various treatments exist.
150 citations,
February 2013 in “Surgical Infections” Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.
147 citations,
November 2020 in “International Journal of Molecular Sciences” Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
145 citations,
November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
140 citations,
February 2020 in “Frontiers in Plant Science” RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.
132 citations,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
124 citations,
June 2020 in “Cell Stem Cell” Fat cells in the skin help start healing and form important repair cells after injury.
123 citations,
December 2015 in “Journal of Neuroendocrinology” New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
122 citations,
July 2005 in “The FASEB journal” Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.
120 citations,
February 2009 in “Apoptosis” Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
116 citations,
September 2020 in “Nature Communications” The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.
115 citations,
November 2004 in “Brain Behavior and Immunity” Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.
109 citations,
January 2011 in “Frontiers in Systems Neuroscience” Choosing the right model order in brain connectivity analysis can affect the detection of differences between healthy individuals and those with seasonal affective disorder.
96 citations,
September 2017 in “Analytica Chimica Acta” Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.