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    Glossary Neural Crest

    group of embryonic cells that form diverse tissues

    The neural crest is a group of cells in vertebrate embryos that emerge from the edges of the neural tube, which later develops into the central nervous system. These cells migrate to various parts of the body and differentiate into a diverse range of tissues, including some types of neurons, glial cells, and even pigment cells in the skin.

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    1. Convergent Genesis of an Adult Neural Crest-Like Dermal Stem Cell from Distinct Developmental Origins Stem cells · 2010 · 106 citations
    2. Human Epidermal Neural Crest Stem Cells (hEPI-NCSC)—Characterization and Directed Differentiation into Osteocytes and Melanocytes Stem Cell Reviews and Reports · 2011 · 91 citations
    3. From neural crest cells to melanocytes: cellular plasticity during development and beyond Cellular and Molecular Life Sciences · 2019 · 66 citations
    4. Existence of Neural Crest–Derived Progenitor Cells in Normal and Fuchs Endothelial Dystrophy Corneal Endothelium American Journal Of Pathology · 2016 · 44 citations
    5. Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1 Development · 2010 · 34 citations
    6. Induction of osteoblastic differentiation of neural crest-derived stem cells from hair follicles PLoS ONE · 2017 · 17 citations
    7. Canine Epidermal Neural Crest Stem Cells: Characterization and Potential as Therapy Candidate for a Large Animal Model of Spinal Cord Injury Stem Cells Translational Medicine · 2014 · 17 citations
    8. Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis Stem cells international · 2019 · 11 citations
    9. Multipotent Neural Crest Stem Cell-Like Cells from Rat Vibrissa Dermal Papilla Induce Neuronal Differentiation of PC12 Cells BioMed research international · 2014 · 10 citations
    10. Heterogeneity of neural crest-derived melanocytes Central European Journal of Biology · 2013 · 8 citations
    11. Developmentally regulated expression of integrin alpha-6 distinguishes neural crest derivatives in the skin Frontiers in Cell and Developmental Biology · 2023 · 5 citations
    12. Generation of Induced Pluripotent Stem Cells from Hair Follicle Bulge Neural Crest Stem Cells Cellular reprogramming · 2014 · 3 citations
    13. Neural crest cells give rise to non-myogenic mesenchymal tissue in the adult murid ear pinna bioRxiv (Cold Spring Harbor Laboratory) · 2023 · 1 citations
    14. The Role of miR-214-3p in Hair Follicle Neural Crest Stem Cell-derived Exosomes in the Repair of Peripheral Nerve Injury 2025
    15. Neural crest cells and their potential therapeutic applications Morphologia · 2021
    16. EGF–FGF2 stimulates the proliferation and improves the neuronal commitment of mouse epidermal neural crest stem cells (EPI-NCSCs) Experimental Cell Research · 2014 · 29 citations
    17. Mouse Epidermal Neural Crest Stem Cell (EPI-NCSC) Cultures Journal of Visualized Experiments · 2008 · 14 citations
    18. Investigating the synergic effects of valproic acid and crocin on BDNF and GDNF expression in epidermal neural crest stem cells Acta Neurobiologiae Experimentalis · 2020 · 10 citations
    19. Prenatal transplantation of epidermal neural crest stem cells in malformation of cortical development mouse model Microscopy Research and Technique · 2016 · 5 citations
    20. Mouse Epidermal Neural Crest Stem Cell (EPI-NCSC) Cultures Journal of Visualized Experiments · 2008 · 3 citations
    21. [Transplanted epidermal neural crest stem cell in a peripheral nerve gap]. PubMed · 2014 · 2 citations
    22. Olig2 positive cells derived from hair follicle neural crest stem cells in rats Journal of chemical neuroanatomy · 2020
    23. Exosomes from Hair Follicle Epidermal Neural Crest Stem Cells Promote Acellular Nerve Allografts to Bridge Rat Facial Nerve Defects Stem Cells and Development · 2022
    24. Human epidermal neural crest stem cells as a source of Schwann cells Development · 2015 · 44 citations
    25. Pluripotent Hair Follicle Neural Crest Stem-Cell-Derived Neurons and Schwann Cells Functionally Repair Sciatic Nerves in Rats Molecular Neurobiology · 2009 · 36 citations
    26. Lithium chloride promotes the odontoblast differentiation of hair follicle neural crest cells by activating Wnt/β‐catenin signaling Cell Biology International · 2014 · 16 citations
    27. Human epidermal neural crest stem cells as candidates for cell-based therapies, disease modeling, and drug discovery Birth defects research · 2014 · 13 citations
    28. Construction of Tissue-Engineered Nerve Conduits Seeded with Neurons Derived from Hair-Follicle Neural Crest Stem Cells Methods in molecular biology · 2016 · 7 citations
    29. The Suppression Effects of Fat Mass and Obesity Associated Gene on the Hair Follicle-Derived Neural Crest Stem Cells Differentiating into Melanocyte by N6-Methyladenosine Modifying Microphthalmia-Associated Transcription Factor International Journal of Stem Cells · 2023 · 4 citations
    30. Differentiation of cultured hair follicle neural crest stem cells into functional melanocytes Heliyon · 2024 · 1 citations