December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
42 citations,
October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
January 2024 in “Frontiers in Bioengineering and Biotechnology” A new method using stem cell membranes to deliver Minoxidil improved hair growth in mice better than Minoxidil alone.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Ezh2 controls skin development by balancing signals for dermal and epidermal growth.
173 citations,
August 2015 in “Developmental cell” The study identified unique genes in hair follicle cells and their environment, suggesting these genes help organize cells for hair growth.
115 citations,
December 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
5 citations,
May 2018 in “Cancer Cell” Less differentiated melanoma cells are more vulnerable to a type of cell death, which could improve cancer treatments.
16 citations,
February 2022 in “Science Advances” Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.
2 citations,
December 2022 in “International journal of molecular sciences” Plucked hairs can be used instead of skin biopsies to study hair traits because they contain specific cells related to hair.
22 citations,
July 2020 in “iScience” Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.
26 citations,
February 2022 in “Journal of pineal research” Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.
14 citations,
March 2016 in “Mechanisms of Development” Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.
1 citations,
August 2023 in “The Journal of Pathology” Different types of skin fibroblasts have unique roles in skin health and disease.
January 2018 in “Contributions to management science” MicroRNAs are crucial for skin development, regeneration, and disease treatment.
4 citations,
June 2023 in “Journal of developmental biology” The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
9 citations,
July 2022 in “Cell reports” Sox2 controls hair color by affecting pigment production in hair follicles.
April 2024 in “Materials today bio” The CuCS/Cur wound dressing helps regenerate nerves and heal deep skin burns by rebuilding hair follicles.
1 citations,
October 2022 in “Biomedicines” Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.
488 citations,
July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
6 citations,
November 2022 in “Development” New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.
161 citations,
August 2012 in “Seminars in cell & developmental biology” Hair growth and development are controlled by specific signaling pathways.
403 citations,
December 2018 in “Cell stem cell” Understanding phenotypic plasticity is crucial for developing effective cancer therapies.
144 citations,
August 2019 in “Cells” The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
11 citations,
April 2013 in “SpringerPlus” Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.
55 citations,
December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” Keratinocytes control how melanocytes work.
75 citations,
January 2009 in “International journal of trichology” Hair grays due to oxidative stress and fewer functioning melanocytes.
111 citations,
January 2007 in “Seminars in cell & developmental biology” Hair, teeth, and mammary glands develop similarly at first but use different genes later.
29 citations,
January 2010 in “Methods in Enzymology” The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.
22 citations,
August 1999 in “Experimental Dermatology” Certain drugs can cause early hair growth in mice by affecting the nerves.
May 2021 in “GSC Advanced Research and Reviews” Hair color is influenced by genetics and can indicate certain health conditions.