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    Glossary Neural Crest Stem Cells

    originate from the neural crest and can become various cell types

    Neural Crest Stem Cells (NCSCs) are a type of multipotent stem cell that originate from the neural crest, a transient structure in vertebrate embryos. These cells have the remarkable ability to differentiate into a diverse range of cell types, including neurons, glial cells, melanocytes, and even some types of connective tissue. This versatility makes them crucial for the development of various tissues and organs, and they are a significant focus in regenerative medicine and developmental biology research.

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    1. Progenitor cells expressing nestin, a neural crest stem cell marker, differentiate into outer root sheath keratinocytes Veterinary Dermatology · 2019 · 12 citations
    2. Multipotent Neural Crest Stem Cell-Like Cells from Rat Vibrissa Dermal Papilla Induce Neuronal Differentiation of PC12 Cells BioMed research international · 2014 · 10 citations
    3. CD34 defines melanocyte stem cell subpopulations with distinct regenerative properties PLOS genetics · 2019 · 41 citations
    4. Existence of Neural Crest–Derived Progenitor Cells in Normal and Fuchs Endothelial Dystrophy Corneal Endothelium American Journal Of Pathology · 2016 · 44 citations
    5. Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles American Journal Of Pathology · 2006 · 344 citations
    6. EGF–FGF2 stimulates the proliferation and improves the neuronal commitment of mouse epidermal neural crest stem cells (EPI-NCSCs) Experimental Cell Research · 2014 · 29 citations
    7. Differentiation of cultured hair follicle neural crest stem cells into functional melanocytes Heliyon · 2024 · 1 citations
    8. CD49fhigh Defines a Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance 2019 · 11 citations
    9. Prenatal transplantation of epidermal neural crest stem cells in malformation of cortical development mouse model Microscopy Research and Technique · 2016 · 5 citations
    10. Induction of osteoblastic differentiation of neural crest-derived stem cells from hair follicles PLoS ONE · 2017 · 17 citations
    11. Human epidermal neural crest stem cells as a source of Schwann cells Development · 2015 · 44 citations
    12. Skin melanocytes: biology and development Postepy Dermatologii I Alergologii · 2013 · 401 citations
    13. Human dermal stem cells differentiate into functional epidermal melanocytes Journal of Cell Science · 2010 · 164 citations
    14. Human Epidermal Neural Crest Stem Cells (hEPI-NCSC)—Characterization and Directed Differentiation into Osteocytes and Melanocytes Stem Cell Reviews and Reports · 2011 · 91 citations
    15. Convergent Genesis of an Adult Neural Crest-Like Dermal Stem Cell from Distinct Developmental Origins Stem cells · 2010 · 106 citations
    16. Experimental dataset for: Hair follicle neural crest stem cell-derived exosomes promote peripheral nerve regeneration via miR-214-3p Mendeley Data · 2026
    17. Experimental dataset for: Hair follicle neural crest stem cell-derived exosomes promote peripheral nerve regeneration via miR-214-3p Mendeley Data · 2026
    18. Caracterização e diferenciação neural in vitro de células-tronco de polpa de dente decíduo humano 2015 · 1 citations
    19. From neural crest cells to melanocytes: cellular plasticity during development and beyond Cellular and Molecular Life Sciences · 2019 · 66 citations
    20. Análise de marcadores de células tronco e progenitores das células de polpa dentária e de vibrissas de camundongos C57BL6. 2017
    21. The in vitro plasticity of hair follicle dermal and mesenchymal stem cells Durham e-Theses (Durham University) · 2008
    22. The beneficial effects of chick embryo extract preconditioning on hair follicle stem cells: A promising strategy to generate Schwann cells Cell proliferation · 2023 · 5 citations
    23. TGF-β Family Signaling in Epithelial Differentiation and Epithelial–Mesenchymal Transition Cold Spring Harbor Perspectives in Biology · 2017 · 82 citations
    24. Uncomplicated differentiation of stem cells into bipolar neurons and myelinating glia Biochemical and Biophysical Research Communications · 2008 · 33 citations
    25. Homing of stem cells to sites of inflammatory brain injury after intracerebral and intravenous administration: a longitudinal imaging study Stem Cell Research & Therapy · 2010 · 87 citations
    26. Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis Stem cells international · 2019 · 11 citations
    27. Olig2 positive cells derived from hair follicle neural crest stem cells in rats Journal of chemical neuroanatomy · 2020
    28. Derivation of Stem Cell-like Cells From Spherical Culture of Astrocytes for Enhanced Neural Repair After Middle Cerebral Artery Occlusion Frontiers in Bioengineering and Biotechnology · 2022 · 1 citations
    29. Molecular heterogeneity of quiescent melanocyte stem cells revealed by single-cell RNA-sequencing bioRxiv (Cold Spring Harbor Laboratory) · 2023
    30. Spatiotemporal Labeling of Melanocytes in Mice International Journal of Molecular Sciences · 2018 · 4 citations