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The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Keratinocytes control how melanocytes work.

Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.

Androgens may block hair growth signals, targeting this could treat hair loss.

Hair follicle stem cells can turn into various cell types and help repair nerves.

Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.

Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

PlncRNA-1 helps hair follicle stem cells grow and develop by controlling a specific cell signaling pathway.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.

Certain drugs can cause early hair growth in mice by affecting the nerves.

Looking at skin can help find and treat serious diseases early.

Hair color is determined by different melanins and changes with age.

PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.

Only skin melanocytes, not other types, can color hair in mice.

Miscanthus sinensis flower extract may help promote hair growth and prevent hair loss.

A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.

Gray hair is caused by reduced melanin production or transfer issues, linked to aging and possibly health conditions, with treatments focusing on color camouflage.

Beige and leaden pigment genes act within melanocytes, affecting pigment patterns.

Mitochondrial problems in tooth cells lead to bad enamel and dentin development in mice.

Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.

A boy's hair loss improved after tumor removal and vitamin D treatment, but hair loss returned despite normal vitamin D and no tumor regrowth.

Certain Ayurvedic herbs may help manage premature greying of hair.

The research found ways to activate melanocyte stem cells for potential treatment of skin depigmentation conditions.

Blocking RANK signaling might help treat metastatic melanoma, but more research is needed.

Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.

Lenalidomide helps hair follicle stem cells turn into melanocytes, which may improve repigmentation in vitiligo.

Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.

Hair color is influenced by genetics and can indicate certain health conditions.