The chapter discusses methods to restore hair.
This article reviews historical and contemporary information about hair transplantation and reports no new research findings, offering guidance on navigating the extensive online content.
48 citations
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September 2020 in “Frontiers in Immunology” In this study, researchers found that loss of OGG1 in a mouse model of systemic lupus erythematosus increased IFN-driven immune responses and aggravated skin lesions, suggesting a protective role for OGG1 in SLE skin disease.
43 citations
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December 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that progesterone reduces neuronal injury from tributyltin exposure in rat hippocampal slices through a mechanism dependent on allopregnanolone and GABAA receptors.
39 citations
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October 2012 in “Headache The Journal of Head and Face Pain” This study reports cutaneous atrophy and alopecia in four patients following greater occipital nerve blockade with triamcinolone and lidocaine, suggesting that alternative steroids may reduce these side effects.
13 citations
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July 2017 in “Annals of Oncology” This study suggests that DNA-neutralizing agents like DNAse I and Resveratrol-Cu might reduce chemotherapy-induced toxicity, although this conclusion is based on a small animal study and needs more research.
9 citations
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February 2025 in “Journal of Nanobiotechnology” In this study, researchers found that using bioinspired nanovesicles derived from inflammation memory-activated epidermal stem cells effectively promoted healing in diabetic wounds by reprogramming neutrophils to an anti-inflammatory phenotype in both laboratory and animal models.
9 citations
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October 2024 in “Heliyon” In this review, the authors discuss the promising role of exosomes from various cell sources as potential cell-free therapies for diabetic foot ulcers, highlighting their therapeutic benefits in wound healing and the challenges faced in their clinical application.
6 citations
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January 2016 in “Open journal of regenerative medicine” This study found that macrophages treated with keratin in vitro were more similar to anti-inflammatory M2 macrophages and reduced astrocyte reactivity, potentially limiting secondary inflammatory damage after spinal cord injury.
2 citations
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December 2022 in “The Journal of Dermatology” This study found that patients with hidradenitis suppurativa had significantly higher levels of cell-free DNA in their serum compared to healthy controls, suggesting its potential as a biomarker for the disease.
1 citations
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July 2023 in “Journal of the European Academy of Dermatology and Venereology” 1 citations
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June 2022 in “Journal of Cosmetic Dermatology” This study in a Korean population identified two novel genetic variants that may increase the risk of androgenetic alopecia, contributing to understanding its genetic basis in non-European populations.
January 2026 in “Journal of Community Medicine and Health Solutions” In this study, the novel topical agent PP405 showed favorable tolerability and increased hair density by over 20% in men with advanced androgenetic alopecia after eight weeks, suggesting a promising potential treatment pending further trials.
September 2025 in “PeerJ” This study found that the genes FCER1A and RGS1 are promising biomarkers for diagnosing systemic lupus erythematosus, with FCER1A downregulated and RGS1 upregulated in patients.
January 2024 in “Authorea (Authorea)” This source suggests that convalescent plasma therapy may interfere with early immune responses in COVID-19 due to exosomes suppressing immune cell activity, but proposes it could potentially help with COVID-19 Long Hauler Syndromes by targeting diverse antigen responses beyond just the spike protein.
This study proposes that neutralizing antibodies and exosomes in convalescent plasma may interfere with early immune responses, potentially explaining limited success of this therapy in active COVID-19 infections.
April 2019 in “Journal of the Endocrine Society” This case study reports a rare instance of ectopic ACTH secretion from a primary lung neuroendocrine tumor in a young woman, highlighting successful diagnosis and treatment following symptoms of Cushing syndrome, with normalization of ACTH, glucose, and cortisol levels post-surgery.
February 2026 in “International Journal of Cosmetic Science” This study found that a novel Mito-Activator Complex, containing nicotinamide and epigallocatechin gallate, significantly increased hair density and growth in a 6-month human trial, with no adverse effects reported, potentially offering a new approach to hair loss treatment through mitochondrial activation.
February 2024 in “The Journal of Dermatology” In this study, dutasteride 0.5 mg was found to provide long-term efficacy and safety in treating androgenetic alopecia in Korean men, with 89.9% showing improvement and 93.9% experiencing prevention of disease progression over at least 5 years.
January 2022 in “IntechOpen eBooks” This review examines lesser-known factors contributing to polycystic ovarian syndrome and reports no new clinical results, emphasizing the need for further research into individualized treatment and prevention strategies.
November 2022 in “The Journal of Urology” This study suggests that adopting the Mark Cuban Cost Plus Drug Company model for purchasing urological medications could have saved Medicare about $1.29 billion in 2020.
64 citations
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October 2018 in “Thérapie” This report describes the enhancement of the French SNIIRAM/SNDS healthcare database through external data linkages, highlighting its potential use in medical research despite complexities in the integration process.
2 citations
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September 2023 in “Aging” In this study, researchers found that Elastic Net DNA methylation clocks are not accurate for distinguishing between individuals or identifying health markers, but measuring biological "noise" in stable cytosines may serve as a potential biomarker of aging and disease.
848 citations
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October 2020 in “International Journal of Molecular Sciences” This review discusses the potential of platelet-rich plasma applications in regenerative medicine and explores recent progress and challenges in translating non-clinical PRP findings into human treatments, but reports no new clinical results.
170 citations
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September 2020 in “Viruses” This review highlights that drug repositioning offers a cost-effective alternative to traditional drug discovery, especially for treating orphan and resistant diseases like COVID-19, by repurposing existing drugs such as Hydroxychloroquine and Remdesivir.
61 citations
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April 2023 in “Bioactive Materials” This review article highlights recent advances in microneedle technology for wound healing and tissue regeneration, discussing various cargo types, structural designs, and fabrication methods, and suggesting guidelines for designing microneedle systems tailored to specific applications.
54 citations
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January 2023 in “Signal Transduction and Targeted Therapy” This review examines integrins as pharmacological targets, discussing current integrin-based therapies and emphasizing the need to understand integrin mechanisms for successful drug development, without reporting new clinical results.
44 citations
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April 2023 in “Frontiers in Molecular Biosciences” This narrative review outlines the diverse symptoms and possible mechanisms behind long COVID, such as immune dysregulation and viral persistence, while discussing ongoing and potential treatments, highlighting the current lack of proven effective therapies.
41 citations
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July 2018 in “Frontiers in Neurology” This study suggests that myotonic dystrophies may qualify as segmental progeroid disorders due to molecular and clinical similarities with typical progeroid syndromes.
37 citations
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February 2024 in “Military Medical Research” In this review, biomaterial-based mechanical strategies were highlighted for their potential to enhance skin regeneration and promote scarless repair, though a comprehensive understanding of their underlying mechanisms is still needed for broader application.