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The document concludes that managing PCOS involves treating symptoms, regulating periods, and reducing health risks, with specific medications for fertility and metabolic issues.

Isotretinoin can cause serious birth defects and needs careful use, especially in pregnant women.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Hormones like testosterone and estrogen significantly affect hair growth and structure.

Ginsenoside Rb1 slows down aging in mice by affecting cell growth, cell death, and metabolism.

A new one-step test can quickly identify skin cancer during surgery.

Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

No single biomarker is reliable enough for diagnosing and assessing SLE.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.

ePUKs could be valuable for regenerative medicine due to their wound healing abilities.

Neurosteroids help regulate oxytocin levels, especially during stress and pregnancy, to protect against premature labor.

HPH-15, a new compound, effectively reduces skin fibrosis in experiments without causing harm.

Topical glucocorticoids thin the skin and change collagen structure.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Zinc helps reduce the severity of depression.

miR-31 regulates hair growth by controlling gene expression in hair follicles.

Sesn2 protects inner ear hair cells from damage by regulating certain cell survival pathways.

Transplanted rat hair follicles grew hair and had increased but not fully restored nerve connections in mice.

Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.