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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Human skin can make serotonin and melatonin, which help protect and maintain it.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Some medicinal plants can help heal wounds and may lead to new treatments.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.