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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.

Hodgkin's lymphoma can show up as hair loss.

Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.

Some skin diseases and their treatments can negatively affect male fertility.

The Drug Ontology was updated to better classify drugs for hypertension, malaria, and opioid abuse, and to allow for more accurate research queries.

A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.

Aging skin shows thinner layers, fewer hair follicles, and new biomarkers like increased space between cells and smaller sebaceous glands.

Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.

Biotin supplements are unnecessary for most people but may help with certain conditions like biotin deficiency, brittle nails, and some hair loss.

The conclusion is that combining social and cultural factors with pharmaceutical research could improve our understanding of how drugs work.

3D microenvironments in microwells improve hair follicle stem cell behavior and hair regeneration.

Herbal hair oils help with hair problems and are safer than synthetic products.

The document concludes that new treatments for hair loss may involve a combination of cosmetics, clinical methods, and genetic approaches.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

Future research should focus on making bioengineered skin that completely restores all skin functions.

Finding functions for unknown GPCRs is hard but key for making new drugs.

Radiotherapy effectively treated a large scalp tumor in an elderly woman, avoiding surgery.

Yoga Nidra improves well-being and reduces anxiety in women with PCOS.

Hair follicle stem cells are important for maintaining healthy skin and interact with many signals.

More research is needed before using brown fat to treat polycystic ovary syndrome.

PCOS may increase the risk of certain cancers.

PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.

PCOS increases the risk of heart disease and type 2 diabetes in women.

Eating a balanced diet with the right vitamins and minerals is important for healthy hair, but too many supplements can be harmful.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.