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Leflunomide is effective for rheumatoid arthritis but has significant side effects.

Blond hair in Solomon Islanders is due to a unique genetic variant, not European ancestry.

Topical minoxidil may not improve the appearance of balding men, according to a letter in this document.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Androgens can help prevent memory problems caused by apoE4.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Skin problems are very common in people with systemic lupus erythematosus and important for diagnosis.

Alopecia is a key indicator of thallium poisoning.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

PLD is an effective and safer alternative for treating breast cancer.

Voriconazole can cause serious side effects, especially in long-term use.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Lichen planus pigmentosus causes dark skin patches and is treated by avoiding triggers and using anti-inflammatory medications.