51 citations,
April 1982 in “Lancet” Most patients with hard-to-treat high blood pressure can be managed effectively with various treatments, but no single treatment is perfect.
50 citations,
September 1975 in “American Heart Journal” Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.
49 citations,
January 1980 in “Journal of Cardiovascular Pharmacology” Minoxidil doesn't increase pericardial disorder risk, but may cause fluid accumulation.
47 citations,
May 2020 in “Cardiovascular Research” The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.
46 citations,
April 1977 in “Southern Medical Journal” Minoxidil causes excessive hair growth, but depilatory agent removes it safely and effectively.
43 citations,
May 1978 in “JAMA” Minoxidil controls blood pressure but may cause kidney damage and needs diuretics to prevent swelling.
37 citations,
April 1979 in “The Journal of Clinical Pharmacology” Minoxidil effectively controls blood pressure but side effects may limit its use.
36 citations,
July 1977 in “The Journal of Pediatrics” Minoxidil helps lower blood pressure in kids with severe hypertension, but may cause temporary excessive hair growth.
35 citations,
July 1981 in “Clinical Pharmacology & Therapeutics” Minoxidil can cause dangerous fluid buildup around the heart.
35 citations,
August 1980 in “Circulation” Minoxidil may cause heart issues in animals and humans.
34 citations,
January 1989 in “Toxicologic Pathology” A study found that minoxidil can damage the hearts of dogs and pigs, cautioning its use in humans.
29 citations,
May 2018 in “Clinical Endocrinology” Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.
27 citations,
August 1984 in “Experimental and Molecular Pathology” 25 citations,
December 1974 in “Clinical Pharmacology & Therapeutics” Propranolol affects heart rate and renin levels in minoxidil-treated patients.
24 citations,
October 2017 in “Biomolecules” Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
24 citations,
May 2012 in “International Journal of Dermatology” The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.
23 citations,
June 1996 in “Toxicology” Older rats more affected by minoxidil's cardiotoxic effects than younger rats.
19 citations,
July 1983 in “American Journal of Kidney Diseases” Minoxidil lowers blood pressure in kids with kidney issues, but use carefully due to side effects.
18 citations,
July 1975 in “Clinical Pharmacology & Therapeutics” Oral minoxidil effectively controls blood pressure quickly and safely.
17 citations,
May 1975 in “Clinical Pharmacology & Therapeutics” 16 citations,
August 2007 in “Histopathology” A woman's rare adrenal tumor caused high testosterone and cortisol levels, which normalized after the tumor was removed.
16 citations,
July 1992 in “The journal of experimental zoology/Journal of experimental zoology” Adrenal glands delay the start of winter fur growth in mink.
15 citations,
January 1995 in “Archives of Dermatological Research” Minoxidil boosts elastin production, potentially helping skin diseases.
14 citations,
April 2009 in “Acta Medica Scandinavica” Minoxidil helps control blood pressure but has side-effects, so it's not for everyone.
14 citations,
October 1977 in “The Lancet” 13 citations,
July 1996 in “Annals of Internal Medicine” International medical graduates outperformed U.S. graduates on an internal medicine exam.
13 citations,
July 1996 in “Annals of Internal Medicine” International medical graduates outperformed U.S. graduates on an internal medicine exam.
11 citations,
March 2007 in “Journal of Hypertension” Minoxidil effectively lowers blood pressure in resistant cases, but needs beta-blocker and diuretic support.
11 citations,
January 1980 in “Southern Medical Journal” Minoxidil effectively treats severe hypertension but has notable side effects.
8 citations,
July 1996 in “Annals of Internal Medicine” Itraconazole may cause low platelet and white blood cell counts.