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Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Taking selenium supplements during chemotherapy may help reduce side effects and improve health markers in ovarian cancer patients.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.

Applying a special compound can promote hair growth without harmful side effects.

Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.

Liposomes could improve how skin care products work but are costly and not very stable.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.

Different types of skin pores should be identified correctly and evaluated with suitable methods for reliable results.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

The document concludes that proper diagnosis and FDA-approved treatments for different types of hair loss exist, but treatments for severe cases often fail and future improvements may focus on hair follicle stem cells.

Imiquimod 5% cream reduced equine sarcoids in most cases.

Myo-inositol may be more effective than metformin for inducing ovulation in women with PCOS.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

Human hair follicles can regenerate after removal, but with low success rate.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.