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Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Growing human skin cells in a 3D environment can stimulate new hair growth.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Different types of skin cells play specific roles in development, healing, and cancer.

Targeted cancer therapies often cause serious skin problems that need careful management.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Stem cell niches support, regulate, and coordinate stem cell functions.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Taking selenium supplements during chemotherapy may help reduce side effects and improve health markers in ovarian cancer patients.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.

Liposomes could improve how skin care products work but are costly and not very stable.

Understanding the mouse hair cycle is crucial for cancer research.